| Baseline | End of study |
---|
All subjects | Â |
---|
(N = 15) |  |
---|
 | Withdrawn | Completed |  | Completed |  |  |
---|
 | (N = 5) | (N = 10) | Pa
| (N = 10) | Difference | Pb
|
---|
 |
Number
| Â | Â |
PS
| 1 | Â | Â | 0 | 2 | 0.79#
| 4 | Â | 0.15#
|
 | 2 |  |  | 2 | 4 |  | 4 |  |  |
 | 3 |  |  | 3 | 4 |  | 2 |  |  |
 |
Mean (SD)
| Â | Â |
6MWT
| m |  | 257(160) | 166 (138) | 303 (157) | 0.11 | 282 (171) | −21.1 (167.7) | 0.70 |
 | % |  | 50.2 (32.2) | 31.0(24.6) | 59.8(32.2) | 0.08 | 56.0(34.5) | −3.8 (33.3) | 0.73 |
STS
| s |  | 8.0(4.3) | 7.6 (3.4) | 8.2 (4.8) | 0.80 | 7.0(3.3) | −1.2 (3.4) | 0.30 |
 | S-score |  | 2.6(2.4) | 2.2 (2.0) | 2.7 (2.2) | 0.69 | 2.0(1.8) | −0.7 (2.0) | 0.30 |
- Notes: Performance status (PS), six-minute walk distance (6MWT) in metres (m) and expressed as % predicted (from [21]), Sit-to-stand (STS) test expressed as seconds (s) and as a standard score (S-score) value calculated using age range-specific mean and standard deviations for healthy controls (from [22]): positive scores indicates STS S-scores above the mean. Pa: #Fisher’s exact (for counts) or unpaired t-test (for means) comparing baseline results for patients withdrawn and patients who completed study. Pb: #Fisher’s exact (for counts) or paired t-test (for means) comparing baseline and final test results for patients who completed the study.