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Table 2 Factors significantly associated with survival in multiple Cox regression analysis

From: The effect on survival of continuing chemotherapy to near death

Variables HR (95%CI) P-value
Receipt of chemotherapy No chemotherapy 1.00 - -
  Standard chemotherapy 0.80 (0.76, 0.83) < 0.001
  Aggressive-approach chemotherapy 0.82 (0.72, 0.92) < 0.001
Age at diagnosis 65 1.00 - -
  Each increasing year 1.01 (1.00, 1.01) < 0.001
Gender Female 1.00 - -
  Male 1.09 (1.05, 1.14) < 0.001
Charlson comorbidity index 0 1.00 - -
  1 1.16 (1.09, 1.23) < 0.001
  2 ≤ 1.28 (1.18, 1.38) < 0.001
Region of tumor registries Northeast 1.00 - -
  South - - n.s.
  Midwest - - n.s.
  West 1.08 (1.03, 1.13) < 0.001
Socioeconomic status Lowest quintile 1.00 - -
  Each increasing quintile - - n.s.
Teaching hospital No 1.00 - -
  Yes - - n.s.
Year of death 1991 1.00 - -
  1992 1.11 (1.04, 1.19) < 0.01
  1993 - - n.s.
  1994 - - n.s.
  1995 - - n.s.
  1996 - - n.s.
  1997 - - n.s.
  1998 0.91 (0.84, 0.97) < 0.01
  1999 0.89 (0.82, 0.96) < 0.01
  1. Abbreviation: HR, hazard ratio; CI, confidence interval; n.s., not significant.
  2. NOTE: Stepwise selection was used. Race/ethnicity, and living in urban region were not found to be significant predictors of survival in univariate analysis (P-value > 0.20).