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Table 2 Factors significantly associated with survival in multiple Cox regression analysis

From: The effect on survival of continuing chemotherapy to near death

Variables

HR

(95%CI)

P-value

Receipt of chemotherapy

No chemotherapy

1.00

-

-

 

Standard chemotherapy

0.80

(0.76, 0.83)

< 0.001

 

Aggressive-approach chemotherapy

0.82

(0.72, 0.92)

< 0.001

Age at diagnosis

65

1.00

-

-

 

Each increasing year

1.01

(1.00, 1.01)

< 0.001

Gender

Female

1.00

-

-

 

Male

1.09

(1.05, 1.14)

< 0.001

Charlson comorbidity index

0

1.00

-

-

 

1

1.16

(1.09, 1.23)

< 0.001

 

2 ≤

1.28

(1.18, 1.38)

< 0.001

Region of tumor registries

Northeast

1.00

-

-

 

South

-

-

n.s.

 

Midwest

-

-

n.s.

 

West

1.08

(1.03, 1.13)

< 0.001

Socioeconomic status

Lowest quintile

1.00

-

-

 

Each increasing quintile

-

-

n.s.

Teaching hospital

No

1.00

-

-

 

Yes

-

-

n.s.

Year of death

1991

1.00

-

-

 

1992

1.11

(1.04, 1.19)

< 0.01

 

1993

-

-

n.s.

 

1994

-

-

n.s.

 

1995

-

-

n.s.

 

1996

-

-

n.s.

 

1997

-

-

n.s.

 

1998

0.91

(0.84, 0.97)

< 0.01

 

1999

0.89

(0.82, 0.96)

< 0.01

  1. Abbreviation: HR, hazard ratio; CI, confidence interval; n.s., not significant.
  2. NOTE: Stepwise selection was used. Race/ethnicity, and living in urban region were not found to be significant predictors of survival in univariate analysis (P-value > 0.20).