Table 1 Details of cases recalled by physicians where nebulised frusemide was used
| Â | Age | Sex | Primary diagnosis | Main problem causing breathlessness | Previous therapies for breathlessness | Impression of clinical efficacy | Comments |
|---|---|---|---|---|---|---|---|
Case 1 | 70 | Female | NSCL cancer with COPD | Bronchial obstruction | Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics | Possible improvement | No comments provided |
Case 2 | 78 | Male | Pulmonary oedema | Cardiac failure | Oxygen, Opioids, Benzodiazepines | Unsure of any benefit | No comments provided |
Case 3 | 60 | Female | CRC, lung metastases, pleural effusion, lymphangitis | Pleural effusion, lymphangitis | Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Drainage of pleural effusion | Possible improvement | No comments provided |
Case 4 | 84 | Male | Respiratory failure, History of AF & cardiomyopathy | Pulmonary fibrosis and some mild LVF | Oxygen, Opioids, Nebulised atrovent, Low dose midazolam | Obvious improvement | No comments provided |
Case 5 | 70’s | Male | COPD, Lung cancer | COPD, Lung metastases | Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics | Possible improvement | No comments provided |
Case 6 | 65 | Male | Not reported | Not reported | Oxygen, Opioids, Steroids, Benzodiazepines | Possible improvement frusemide | No comments provided |
Case 7 | 60’s | Female | Stage IV NSCLC | Cardiac failure | Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics | Possible improvement | No comments provided |
Case 8 | 37 | Female | Lung cancer | Local disease, airway compromise, effusion | Oxygen, Opioids, Steroids, Bronchodilators | Obvious improvement | She was quite anxious and benzo’s used helped significantly but further improvement seen after adding lasix as well |
Case 9 | 72 | Female | Metastatic vulval cancer | Pleural effusion | Oxygen, Opioids, Steroids, Glycopyrolate | Obvious improvement | Within 20 minutes, patient came out of unconsciousness. I am considering using now as first line with atrovent when acute episode occurs after chronic control. |
Case 10 | 70’s | Male | Respiratory failure | End stage COPD | Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics | Obvious improvement | Addition of nebulised frusemide improved difficult dyspnea, where all other modalities had been tried; |