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Table 5 The intensity of the worst pain, OMED, performance status, and Karnofsky index at baseline, the CT, d8, d15 and d30 after radiotherapy treatment

From: Early evaluation predicts pain relief of irradiated bone metastases: a single-center prospective study

 

BT

Evaluation time

Results

P*

Median worst pain (range)

7 (1–10)

CT

5 (0–10)

0.001

  

D8

3 (0–10)

<0.001

  

D15

3 (0–10)

<0.001

  

D30

3 (0–10)

<0.001

Median/Mean OMED (mg) (range)

40/90 (0–920)

CT

40/111.1 (0–720)

0.93

  

D8

30/65.7 (0–380)

0.64

  

D15

30/75.9 (0–480)

0.47

  

D30

40/91.2 (0–570)

0.96

WHO PS (range)

2 (0–4)

CT

2 (0–4)

0.003

  

D8

2 (0–4)

0.004

  

D15

2 (0–4)

0.011

  

D30

2 (0–4)

0.003

KPS (range)

70 (30–100)

CT

70 (30–100)

0.001

  

D8

70 (30–90)

0.001

  

D15

70 (30–100)

0.006

  

D30

70 (30–100)

0.002

  1. Abbreviations: BT: beginning of treatment; CT: completion of treatment; KPS: karnofsky performance status; OMED: oral morphine equivalent dose; WHO PS: world health organization performance status.