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Table 6 Studies reporting effectiveness and measurement of effectiveness of levomepromazine

From: Evidence for the use of Levomepromazine for symptom control in the palliative care setting: a systematic review

Indication Reference Number of patients under study Number of patients receiving levomepromazine Effect
sedation Alonso-Babarro [31] 29 2 100% (defined as symptom control was achieved, consciousness (consciousness was 5 or greater using the Ramsay scale and no emergency calls during the PS process)
nausea Eisenchlas [13] 70 70 86% (categorized as responders if NRS score decreased by 6+ from the baseline score)
nausea Kennett [50] 65 65 62.3% (14 patients met the definition of a complete response and 19 a partial response)
nausea Higi [51] 113 113 62% (fully protected from nausea and vomiting)
nausea Oliver [41] 675 15 86% (no data about how effectiveness was measured)
nausea Twycross [55] 29 29 83% (no data about how effectiveness was measured, study not included in our review)
delirium Fainsinger [38] 1 1 0% (ineffective in treating the patient’s delirium and thus discontinued after 48 hours)
agitation Oliver [41] 675 49 67% (no data about how effectiveness was measured)
pain Oliver [41] 675 16 94% (no data about how effectiveness was measured)