Table 6 Studies reporting effectiveness and measurement of effectiveness of levomepromazine
Indication | Reference | Number of patients under study | Number of patients receiving levomepromazine | Effect |
|---|---|---|---|---|
sedation | Alonso-Babarro [31] | 29 | 2 | 100% (defined as symptom control was achieved, consciousness (consciousness was 5 or greater using the Ramsay scale and no emergency calls during the PS process) |
nausea | Eisenchlas [13] | 70 | 70 | 86% (categorized as responders if NRS score decreased by 6+ from the baseline score) |
nausea | Kennett [50] | 65 | 65 | 62.3% (14 patients met the definition of a complete response and 19 a partial response) |
nausea | Higi [51] | 113 | 113 | 62% (fully protected from nausea and vomiting) |
nausea | Oliver [41] | 675 | 15 | 86% (no data about how effectiveness was measured) |
nausea | Twycross [55] | 29 | 29 | 83% (no data about how effectiveness was measured, study not included in our review) |
delirium | Fainsinger [38] | 1 | 1 | 0% (ineffective in treating the patient’s delirium and thus discontinued after 48 hours) |
agitation | Oliver [41] | 675 | 49 | 67% (no data about how effectiveness was measured) |
pain | Oliver [41] | 675 | 16 | 94% (no data about how effectiveness was measured) |