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Table 2 Risk factors associated with depressive symptoms (DRS 3+) comparison of complete case and multiple imputation analyses (Model with CHESS b as Mortality Measure)

From: Prevalence and risk factors of depressive symptoms in a Canadian palliative home care population: a cross-sectional study

Independent variable

Complete case analysis (n = 3734) Adjusted odds ratio (95% confidence limit)

Multiple imputation (n = 5144) Pooled odds ratios (Pooled 95% confidence limit)

Life satisfaction a

  

Low

3.070 (2.37-3.98)

3.01 (2.37-3.82)

High

Reference

Reference

CHESS b

  

2+

2.88 (1.79-4.62)

2.122 (1.42-3.18)

0-1

Reference

Reference

Sleep disorders c

  

Severe

2.78 (2.14-3.60)

2.56 (2.05-3.19)

Moderate

1.52 (1.10-2.11)

1.56 (1.18-2.06)

Minimal

Reference

Reference

Pain scale

  

2+

2.18 (1.64-2.89)

1.73 (1.35-2.22)

0-1

Reference

Reference

Signs of caregiver distress

  

Yes

1.93 (1.51-2.45)

2.01 (1.62-2.51)

No

Reference

Reference

Gender

  

Female

1.42 (1.13-1.79)

1.37 (1.11-1.68)

Male

Reference

Reference

Cognitive impairment

  

CPSd 2+

N/Se

1.45 (1.13-1.87)

0-1

Reference

Gastrointestinal symptoms

  

Moderate-severe

N/Se

1.27 (1.03-1.55)

Minimal

Reference

Goodness of fit

  

C statistic

0.77

0.77 (0.75-0.77)f

Hosmer & Lemeshow -χ 2

6.97

5.27(1.5-14.1)f

-p

0.54

0.73 (0.08-0.99)f

-df

8

8 (8-8)f

  1. a“High” life satisfaction indicates that the patient has all 5 of the following conditions present: a sense of completion, a sense of progress towards completion, acceptance of the situation, inner strengths that can be encouraged/nurtured AND a positive outlook. “Low” life satisfaction” indicates that one or more of the 5 conditions are absent in the patient.
  2. bCHESS = Changes in Health and End-Stage Disease Signs and Symptoms.
  3. c“Sleep disorders” is a composite (summative) measure based on two items: too little sleep (5 severity levels ranging from 0 to 4) and too much sleep (5 severity levels ranging from 0 to 4). “Severe” sleep disorders represent scores of 4+, “moderate” are scores of 2 or 3, and “minimal” are scores of 0 or 1.
  4. dCPS = Cognitive Performance Scale.
  5. eN/S = Not significant at alpha = 0.05 level.
  6. fMean (Minimum-Maximum).