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Table 3 Dose of oral oxycodone and transdermal fentanyl matrix patch at day 0, 8 and 15 (N = 49)

From: Opioid switch from low dose of oral oxycodone to transdermal fentanyl matrix patch for patients with stable thoracic malignancy-related pain

 

Day 1

Day 8

Day 15

Opioids

Oral oxycodone

Fentanyl patch

Fentanyl patch

Dose

   

 Mean ± SD

14.7 ± 4.1 mg/day

13.7 ± 4.8 μg/h

15.5 ± 6.0 μg/h

Patients’ distribution (N)

10 mg/day

18

12.5 μg/h

44

12.5 μg/h

38

15 mg/day

16

18.8 μg/h*

1

18.8 μg/h*

1

20 mg/day

15

25.0 μg/h

3

25.0 μg/h

9

  

37.5 μg/h

1

37.5 μg/h

1

  1. All patients were switched from oral oxycodone to 12.5 μg/h of fentanyl matrix patch at day 1.
  2. *Half-side application procedure of fentanyl matrix patch was not defined in our protocol.
  3. SD; standard deviation.