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Table 4 Change of numeric rating scale (NRS) of pain intensity and use of rescue immediate-release oxycodone

From: Opioid switch from low dose of oral oxycodone to transdermal fentanyl matrix patch for patients with stable thoracic malignancy-related pain

 

Day 1

Day 8

Day 15

p-valuea

NRS pain intensity (N = 49)

   

0.15

 Mean ± SD

2.2 ± 1.4

2.1 ± 1.5

1.9 ± 1.4

 Median (range)

2 (0 - 6)

2 (0 - 7)

2 (0 - 6)

 NRS 0 – 3 / ≥ 4

43/6

41/8

43/6

Immediate-release oxycodone (mg / day) (N = 48)b

   

0.36

 Mean ± SD

1.9 ± 2.2

2.7 ± 3.5

2.2 ± 2.7

 Median (range)

2.5 (0 - 10)

2.5 (0 - 15)

1.75 (0 - 10)

  1. SD; standard deviation.
  2. aFriedman test.
  3. bOne patient was excluded from analysis of rescue use because of missing data throughout all the three observation points. The remaining 48 patients completed data collection.