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Table 7 Dose ranges of corticosteroids prescribed by indication

From: Corticosteroid prescribing in palliative care settings: a retrospective analysis in New Zealand

Drug prescribed by indication (Number of prescribing events)

Median (IQR) starting dose mg

Dose range mg

Median (IQR) final dose mg

1. Non-specific

   

Pred (59)

20 (20)

5 - 60

20 (20)

Meth (3)

125 (0)

125 - 125

125 (0)

Dex (67)

4 (4)

1 - 8

4 (4)

2. Neurological

   

Pred (0)

-

-

-

Meth (6)

125 (0)

80 - 125

125 (0)

Dex (71)

8 (8)

2 - 16

8 (8)

3. Capsular stretching

   

Pred (1)

20 (0)

20 - 20

20 (0)

Meth (0)

-

-

-

Dex (12)

8 (4)

4 - 12

8 (4)

4. Soft tissue infiltration

   

Pred (1)

20 (0)

20 - 20

20 (0)

Meth (7)

125 (0)

125 - 125

125 (0)

Dex (32)

8 (4)

4 - 16

8 (4)

5. Tenesmus

   

Pred (0)

-

-

-

Meth (0)

-

-

-

Dex (2)

8 (0)

8 - 8

8 (0)

6. Inflammation s/c sites

   

Pred (0)

-

-

-

Meth (0)

-

-

-

Dex (10)

0.75 (0.5)

0.5 - 1

1 (0.5)

7. Not clear/other

   

Pred (3)

10 (0)

6 - 80

10 (0)

Meth (1)

1000** (0)

1000 - 1000**

1000** (0)

Dex (24)

8 (4)

1 - 32

4 (4)

8. Chemotherapy

   

Pred (2)

15(0)

10 - 20

15 (0)

Meth (1)

125 (0)

125 - 125

125 (0)

Dex (6)

12 (8)

4 - 16

8 (6)

Total*

   

Pred (66, 21.5%)

20 (20)

5 - 80

20 (20)

Meth (18, 5.8%)

125 (0)

80 - 1000**

125 (0)

Dex (224, 72.7%)

8 (4)

1 - 40

8 (4)

  1. Key: IQR: Interquartile range; Pred: prednisone; Meth: methylprednisolone; Dex: dexamethasone.
  2. *308 of 312 corticosteroid prescribing events are reported (four missing sets of data).
  3. **There was a single instance of methylprednisolone being prescribed at a dose of 1000 mg; the reason for this dose was not recorded in the notes.