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Table 3 Morphine equivalent daily dose by time in subjects with intermittent exposure

From: Dose patterns in commercially insured subjects chronically exposed to opioids: a large cohort study in the United States

Years

Number of subjects

Mean ± SD

Median

Min

Max

P25

P75

P95

Half year

48367

62.48 ± 76.43

50.00

0.25

2700.00

37.50

69.17

112.50

> 6 months to 1 year

22494

57.61 ± 85.68

45.00

0.33

6666.67

31.50

65.16

112.50

> 1 to 1.5 years

19130

56.07 ± 69.1

45.00

0.50

2250.00

30.00

64.11

112.50

> 1.5 to 2 years

15553

56.97 ± 73.8

45.00

0.50

2025.00

30.00

65.00

112.50

> 2 to 2.5 years

11588

58.45 ± 69.05

46.15

0.67

1920.00

30.00

67.50

113.44

> 2.5 to 3 years

8119

60.73 ± 82.99

46.88

0.67

1920.00

30.94

67.50

120.00

> 3 to 3. 5 years

5824

58.23 ± 81.27

45.00

1.56

2660.63

30.00

64.29

112.50

> 3. 5 to 4 years

4677

55.71 ± 75.7

45.00

2.50

1808.04

30.00

60.00

112.50

> 4 to 4.5 years

4619

58.57 ± 87.44

45.00

2.50

2025.00

30.00

60.00

120.00

> 4.5 to 5 years

4111

59.42 ± 100.09

45.00

2.50

2700.00

30.00

60.00

112.50

> 5 to 5.5 years

3418

58.56 ± 96.34

45.00

2.50

3535.12

30.00

60.00

120.00

> 5.5 to 6 years

3301

62.96 ± 113.2

45.00

2.50

2890.19

30.00

61.25

120.00

> 6 to 6.5 years

3225

61.66 ± 109.87

45.00

2.45

3368.28

30.00

62.00

120.00

> 6.5 to 7 years

3031

61.81 ± 101.48

45.00

2.50

2239.86

30.00

60.99

114.28

> 7 to 7.5 years

1837

64.44 ± 116.78

45.00

3.75

2695.92

30.00

60.00

128.57

> 7.5 to 8 years

714

62.71 ± 103.76

45.00

4.17

1350.00

30.00

56.25

146.93

> 8 years

179

72.52 ± 124.42

46.32

6.94

937.50

28.75

60.00

300.00

  1. SD, standard deviation; P25, 25th percentile; P75; 75th percentile; P95; 95th percentile