Time period | Number of subjects who did not continue | Median dose in subjects who did not continue | Number of subjects who continued exposure | Median dose in subjects who continued exposure |
---|---|---|---|---|
Half year | 166 | 56.25 | 453 | 45.0 |
> 6 months to 1 year | 200 | 48.21 | 253 | 44.4 |
> 1 to 1.5 years | 107 | 51.45 | 145 | 45.0 |
> 1.5 to 2 years | 60 | 46.07 | 86 | 49.75 |
> 2 to 2.5 years | 48 | 45.67 | 38 | 60.0 |
> 2.5 to 3 years | 14 | 75.5 | 24 | 54.06 |
> 3 to 3. 5 years | 5 | 60 | 19 | 52.2 |
> 3. 5 to 4 years | 2 | 47.14 | 17 | 45.0 |
> 4 to 4.5 years | 4 | 30.52 | 13 | 60.0 |
> 4.5 to 5 years | 4 | 37.5 | 9 | 96.0 |
> 5 to 5.5 years | 0 | -- | 9 | 156.4 |
> 5.5 to 6 years | 1 | 240.0 | 8 | 120.0 |
> 6 to 6.5 years | 1 | 240.0 | 7 | 75.0 |
> 6.5 to 7 years | 4 | 49.8 | 3 | 210.0 |
> 7 to 7.5 years | 1 | 381.7 | 2 | 123.4 |
> 7.5 to 8 years | 1 | 210.0 | 1 | 45.0 |
Median dose | Â | 56.25 | Â | 45.0 |