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Table 4 Estimates from GEEb modles of indicators of sleep disturbance, edema, uncomfortable, depression and anxiety

From: Symptom severity of patients with advanced cancer in palliative care unit: longitudinal assessments of symptoms improvement

 

Sleep disturbance

Edema

Uncomfortable

Depression

Anxiety

 

N

β(SE)a

P-value

β(SE)a

P-value

β(SE)a

P-value

β(SE)a

P-value

β(SE)a

P-value

Age, year

           

  < 65

 

Reference

-

Reference

-

Reference

-

Reference

-

Reference

-

  ≥ 65

 

−0.39 (0.11)

< 0.001

−0.26 (0.15)

0.093

−0.08(0.11)

0.510

−0.52 (0.10)

< 0.001

−0.80 (0.12)

< 0.001

Gender

           

 Male

480

Reference

-

Reference

-

Reference

-

Reference

-

Reference

-

 Female

344

(0.07)

0.664

0.15 (0.16)

0.046

−0.06 (0.09)

0.548

0.35 (0.11)

< 0.001

0.77 (0.28)

0.005

Cancer

           

 Lung cancer

150

Reference

-

Reference

-

Reference

-

Reference

-

Reference

-

 Gastrointestinal cancer

267

0.37 (0.14)

0.008

0.59 (0.16)

< 0.001

0.24 (0.16)

0.126

0.39 (0.15)

0.010

0.35(0.14)

0.012

 Breast cancer

55

0.36 (0.37)

0.337

1.43 (0.64)

0.026

0.19 (0.28)

0.502

−0.13 (0.20)

0.527

−0.61 (0.20)

0.002

 Genitourinary cancer

108

0.12 (0.19)

0.518

0.82 (0.21)

< 0.001

0.16 (0.20)

0.419

0.22 (0.19)

0.252

0.04(0.17)

0.836

 Head, neck, and oral cancer

185

−0.03 (0.20)

0.881

−1.02 (0.23)

< 0.001

0.07 (0.19)

0.695

0.20(0.16)

0.215

0.34 (0.21)

0.105

 Other cancers

59

0.58 (0.21)

0.006

3.89 (0.54)

< 0.001

139.87(0.19)

<0.001

0.26 (0.19)

0.166

3.08 (0.20)

<0.001

Day of palliative care

           

 1

822

Reference

-

Reference

-

Reference

-

Reference

-

Reference

-

 3

824

−0.30 (0.04)

< 0.001

−0.11 (0.02)

< 0.001

−0.12 (0.04)

0.003

−0.20 (0.03)

< 0.001

−0.10 (0.02)

< 0.001

 5

823

−0.41(0.05)

< 0.001

−0.10 (0.02)

< 0.001

−0.17 (0.05)

< 0.001

−0.28 (0.04)

< 0.001

−0.02 (0.03)

0.452

 7

822

−0.66 (0.07)

< 0.001

0.10 (0.07)

0.135

−0.20 (0.06)

0.001

−0.63 (0.06)

< 0.001

−1.24 (0.05)

< 0.001

  1. a Adjusted mean difference compared to referent group. bGEE generalized estimating equation