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Table 9 Confidence in estimates of healthcare professionals’ emotional burden associated with the practice of CDS

From: The impact of the inpatient practice of continuous deep sedation until death on healthcare professionals’ emotional well-being: a systematic review

Outcome

No of studies

Risk of bias

Imprecision

Heterogeneity

Applicability

Confidencea

  

0

0

−1

−1

+ooo; low

CDS-related burden in physicians

1, Morita T, 2002 [37]

Confounding:

Physicians’ concerns regardless of patients characteristics and other confounders

Physicians’ burden related to choose CDS as treatment option for specific vignettes

Low response rate 49.6%

Variability in mean scores within and between Maslach Burnout Inventory subscales of emotional exhaustion and depersonalization

Variability in prevalence of physicians’ concerns ranging from 1.6-48%

Population:

Japanese oncologists and palliative care specialists with experience in sedation for cancer patients

Intervention:

CDS for cancer patients in vignettes with family support and clinical survival prediction of less than 3 weeks

Comparator:

Physicians choosing CDS as strong treatment option vs. others

Outcome:

Self-reported

Not clear, if patient-specific

No long-term associations possible

 
  

−1

0

−1

0

+ooo; low

CDS-related burden in nurses

2,

Morita T, 2004 [38]

Rietjens JAC, 2007 [39]

Study limitations:

Validity of outcome measures

Confounding:

Stressors influencing general wish to leave current work, R2 = .24

Selection Bias:

Study does not include burdened nurses who already left their current work due to CDS

Recall Bias:

A memorable case up to 5 years in the past

Nurses’ wish to leave current work as single item questions

Heterogeneity in targeted psychological outcome

Variability in prevalence on single item level and across outcomes

Population:

Japanese & Dutch oncology and palliative care nurses with experience in the practice of CDS

Intervention:

CDS for cancer patients predominantly

Comparator:

Nurses with low-level burden vs. high-level burden

Outcome:

Self-reported

Overall burden

No long-term associations possible

 
  1. Note. CDS Continuous deep sedation
  2. aGRADE Working Group grades of evidence. High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate