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Table 4 Caregiver-reported Outcomes - Change from Baseline to 24 weeks (Adjusted for BCOS)

From: Engaging patients and families to create a feasible clinical trial integrating palliative and heart failure care: results of the ENABLE CHF-PC pilot clinical trial

 

All caregivers

Dartmouth

UAB

 

Mean (SE)

p *

Effect size†

Mean (SE)

p *

Effect size†

Mean (SE)

p *

Effect size†

BCOS score

3.70 (2.0)

0.07

0.40

2.30 (2.2)

0.30

0.25

6.70 (3.8)

0.09

0.73

HADS

         

 Anxiety

−0.20 (0.5)

0.69

−0.07

0.10 (0.7)

0.86

0.03

−0.70 (0.9)

0.42

−0.23

 Depression

−1.30 (0.7)

0.08

−0.32

−1.10 (0.9)

0.26

−0.27

−1.90 (1.1)

0.11

−0.47

PROMIS

         

 Global Physical Health

1.70 (1.4)

0.21

0.22

1.60 (1.8)

0.38

0.2

1.60 (2.2)

0.45

0.20

 Global Mental Health

1.80 (1.3)

0.18

0.24

1.00 (1.8)

0.57

0.13

3.20 (1.8)

0.08

0.43

MBCB

         

 Objective burden

−1.10 (0.5)

0.02

−0.33

−0.50 (0.6)

0.39

−0.15

−2.10 (0.8)

0.01

−0.63

 Demand burden

−0.60 (0.4)

0.09

−0.28

−0.04 (0.3)

0.22

−0.19

−1.20 (0.8)

0.16

−0.56

 Stress burden

−1.30 (0.4)

0.001

−0.58

−1.40 (0.5)

0.003

−0.62

−1.40 (0.7)

0.07

−0.62

 Total Score

−3.10 (1.0)

0.002

−0.53

−2.40 (1.0)

0.03

−0.41

−4.60 (2.0)

0.03

−0.78

PAC

         

 Self-affirmation

0.40 (0.8)

0.58

0.11

0.30 (0.9)

0.70

0.08

0.60 (1.4)

0.68

0.16

 Outlook on life

0.40 (0.4)

0.41

0.16

0.50 (0.6)

0.41

0.20

0.40 (0.7)

0.61

0.16

 PAC Total

0.90 (1.2)

0.43

0.15

0.90 (1.4)

0.52

0.15

1.10 (2.0)

0.57

0.19

  1. Abbreviations: SE standard error, BCOS Bakas Caregiving Outcomes Scale, HADS Hospital Anxiety and Depression Scale, PROMIS Patient Reported Outcomes Measurement Information System, MBCB Montgomery Borgatta Caregiver Burden Scale, PAC Positive Aspects of Caregiving
  2. * p-values from t-test or Fisher’s exact tests, as appropriate
  3. †Effect size: Cohen’s d or d-equivalent; small: d ~ 0.2, medium d ~ 0.5, large d ~ 0.8
  4. All change estimates were adjusted for the baseline measures most strongly associated with caregiver attrition: caregiver education, baseline BCOS score and baseline MBCB - objective burden subscale
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BMC Palliative Care

ISSN: 1472-684X

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