Skip to main content

Table 1 Characteristics of patients who were offered first-line chemotherapy, whochose ASC or chemotherapy

From: Exploring the characteristics of patients with mesothelioma who chose active symptom control over chemotherapy as first-line treatment: a prospective, observational, single centre study

 

Chose chemotherapy

Chose ASC

p

Total (n = 139)

93 (66.9)

46 (33.1)

 

Sex, n (%)

 Male

83 (89.2)

35 (76.1)

0.041

 Female

10 (10.8)

11 (23.9)

 

Laterality, n (%)

 Right

54 (58.1)

27 (58.7)

 

 Left

39 (41.9)

19 (41.3)

 
   

0.943

Age, mean (SD)

 

68.4 (6.36)

74.4 (7.35)

<0.001

Performance status, n (%)

 0

40 (43.0)

8 (17.4)

 

 1

48 (51.6)

32 (69.6)

 

 2

5 (5.4)

6 (13.0)

 
   

0.005

Histology, n (%)

 Epithelioid

63 (67.7)

36 (78.3)

 

 Sarcomatoid

15 (16.1)

6 (13.0)

 

 Biphasic

9 (9.7)

1 (2.2)

 

 Desmoplastic

2 (2.2)

1 (2.2)

 

 Not specified

4 (4.3)

2 (4.4)

 
   

0.540

IMIG tumour stage, n (%)

 IA

28 (30.1)

15 (32.6)

 

 IB

6 (6.5)

0

 

 II

7 (7.5)

3 (6.5)

 

 IIIA

0

0

 

 IIIB

30 (32.2)

13 (28.2)

 

 IV

10 (10.75)

7 (15.2)

 

 Not documented

12 (12.9)

8 (17.4)

 
   

0.543

Symptoms, n (%)

 Chest pain

38 (40.9)

22 (47.8)

0.435

 Breathlessness

75 (80.7)

39 (84.8)

0.550

 Cough

42 (45.1)

18 (39.1)

0.499

 Systemic symptoms (sweats, weight loss, fatigue)

37 (39.8)

22 (47.8)

0.367

Blood tests, median (IQR)

 Haemoglobin, g/dL

138 (126-150)

132.5 (121-149)

0.263

 Neutrophils, ×109/L

5.73 (4.80-7.00)

5.84 (4.28-7.00)

0.729

 Lymphocytes, ×109/L

1.6 (1.15-2.15)

1.32 (1.00-1.94)

0.076

 Albumin, g/L

35 (31-38)

34 (30-38)

0.456

 Neutrophil Lymphocyte Ratio (NLR)

4.00 (2.73-5.38)

4.18 (3.09-6.38)

0.255

  1. ASC active symptom control, SD standard deviation, IQR interquartile range