Cohort 1 with meeting (n = 25) | Cohort 2 Meeting + file (n = 52) | p value | |
---|---|---|---|
Age at death, mean (+/− SD), median (IQR) (days) | 28.3 (36.4) 14 (36) | 21.7 (25.6) 11 (17.5) | 0.556 |
Death < 1 week, n (%) | 8 (32) | 17 (32.7) | 0.952 |
Birth context, n (%) | |||
Severe hypoxic-ischemic encephalopathy | 4 (16) | 9 (17.3) | 0.445 |
Congenital anomaly | 5 (20) | 5 (9.6) | |
Premature | 7 (28) | 11 (21.2) | |
Weight less than 1000 g | 9 (36) | 27 (51.9) | |
Verhagen classification, n (%) | |||
Class 1 | 0 | 1 (1.9) | 0.654 |
Class 2 | 1 (4) | 3 (5.8) | |
Class 3 | 7 (28) | 9 (17.3) | |
Class 4 | 17 (68) | 39 (75) | |
Parental opinion before meeting | 4 (16.7) | 25 (48.1) | 0.009 |
Pathology prompting the meeting, n (%) | |||
Severe hypoxic-ischemic encephalopathy | 5 (20) | 8 (15.4) | 0.742 |
Other neurological disease | 12 (48) | 30 (57.7) | |
Sepsis | 1 (4) | 3 (5.8) | |
Congenital anomaly | 3 (12) | 6 (11.5) | |
Acute respiratory disease | 1 (4) | 1 (1.9) | |
Other | 3 (12) | 4 (7.5) | |
Cause of death, n (%) | |||
Severe hypoxic-ischemic encephalopathy | 4 (16) | 9 (17.3) | 0.774 |
Other neurological injury | 13 (52) | 27 (51.9) | |
Sepsis | 1 (4) | 2 (3.8) | |
Hemodynamic failure | 2 (8) | 7 (13.5) | |
Congenital anomaly | 4 (16) | 6 (11.5) | |
Respiratory failure | 1 (4) | 1 (1.9) | |
Lifetime according to pathology, median (IQR) | |||
Severe hypoxic-ischemic encephalopathy | 13 (14.5) | 11 (5.5) | 0.337 |
Congenital anomaly | 20 (112.5) | 31 (41) | |
Premature | 15 (37) | 11 (21) | |
Weight < 1000 g | 11 (54.5) | 9 (17) | |
Understanding of end-of -life conditions, n (%) | 21 (84) | 51 (98.1) | 0.019 |
Decision at the end of the meeting, n (%) | |||
Continue treatment | 1 | 0 | 0.318 |
Withhold treatment | 7 | 14 (26.9) | |
Withdraw treatment | 16 | 38 (73.1) | |
Sedation, n (%) | 24 (96) | 49 (94.2) | 0.743 |
Hypnotics | 5 (20) | 25 (48.1) | 0.018 |
Morphine | 23 (92) | 48 (92.3) | 0.962 |
Ventilation support at time of death, n (%) | 6 (24) | 12 (23.1) | 0.929 |
Mechanical ventilation | 5 (20) | 11 (21.2) | 0.864 |
CPAP | 1 (4) | 1 (1.9) | |
High flow nasal canulea | 0 | 0 |