Table 5 Two-way mixed MANCOVA (multivariate) and two-way mixed ANCOVA (univariate) with confounders as covariates

Covariates at T1 and T2

Test statistics

Sig. 2-tailed

Test statistics

Sig. 2-tailed

Effect size

Test statistics

Sig. 2-tailed

Effect size

Effect

F(2, 12)

p

F(1, 13)

p

r

F(1, 13)

p

r

Pain

Group

0.23

0.79

0.49

0.50

0.19

0.32

0.58

0.15

Time

4.90

0.028*

8.79

0.011*

0.64

1.73

0.21

0.34

Group x time

5.31

0.022*

9.15

0.010*

0.64

1.54

0.24

0.33

AEDL

Group

0.21

0.81

0.09

0.77

0.08

0.08

0.78

0.08

Time

3.44

0.066⁺

7.20

0.019*

0.60

2.61

0.13

0.41

Group x time

5.32

0.022*

9.48

0.009*

0.65

1.60

0.23

0.33

Psychooncological treatment (minutes)

Group

0.67

0.53

1.45

0.25

0.32

0.48

0.50

0.19

Time

7.77

0.007*

16.76

0.001*

0.75

4.60

0.051⁺

0.51

Group x time

4.27

0.040*

8.22

0.013*

0.62

0.68

0.43

0.22

Days with antidepressants

Group

0.10

0.91

0.22

0.65

0.13

0.10

0.76

0.09

Time

2.43

0.13

4.48

0.054⁺

0.51

0.61

0.45

0.21

Group x time

4.95

0.027*

9.39

0.009*

0.65

1.51

0.24

0.32

Palliative care treatment (days)

Group

0.15

0.86

0.32

0.58

0.15

0.18

0.68

0.12

Time

2.66

0.11

4.71

0.049*

0.52

4.95

0.044*

0.53

Group x time

4.41

0.037*

6.89

0.021*

0.59

0.33

0.58

0.16