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Table 3 Sedation practices according to medical unit and indication

From: Midazolam sedation in palliative medicine: retrospective study in a French center for cancer control

CharacteristicsMedical unitIndication 
 Other unit
(N = 37)
PCU
(N = 17)
p-valueImmediate
risk of death
(N = 25)
Refractory
Symptom
(N = 26)
p-value
Indication
 Immediate risk of death1951.4%635.3%0.27  
 Refractory symptom1745.9%952.9%      
 Existential suffering12.7%211.8%      
Relief of the patient
 Unrelieved722.6%00.0%0.1329.5%522.7%0.48
 Relieved2271.0%1493.3% 1885.7%1568.2% 
 Partially relieved26.5%16.7% 14.8%29.1% 
 Unknown6 2  4 4  
Information of the patient1129.7%1164.7%0.0151248.0%726.9%0.12
Information of the family2464.9%1588.2%0.112080.0%1661.5%0.15
Consent of the patient821.6%952.9%0.021936.0%519.2%0.18
Collegiality1129.7%952.9%0.10936.0%830.8%0.69
On-call duty2054.1%1058.8%0.741560.0%1557.7%0.87
Second sedation718.9%423.5%0.73520.0%519.2%1.00
Correspondence2156.8%1694.1%0.0061768.0%1765.4%0.84
Probable sedation513.5%15.9%0.65416.0%27.7%0.42
Continuous sedation3697.3%17100.0%1.0025100.0%2596.2%1.00
Titration1232.4%1270.6%0.0091040.0%1246.2%0.66
Early prescription513.5%1058.8%0.001624.0%934.6%0.41
Associated opioids3286.5%17100.0%0.172392.0%2388.5%1.00
Induction dose (mg)N = 14 N = 12 0.74N = 10 N = 13 0.35
 Median (range)3.0(0.5–10)3.0(0.5–10) 2.5(0.5–8)3.0(0.5–10) 
 Mean (sd)3.8(3.3)4.0(3) 2.9(2.2)4.5(3.8) 
Maintenance dose (mg/h)N = 37 N = 17 0.20N = 25 N = 26 0.22
 Median (range)1(0.2–7)1.2(0.2–5) 0.6(0.2–7)1.1(0.2–5) 
 Mean (sd)1.3(1.4)1.8(1.5) 1.2(1.5)1.7(1.5) 
Dose at the time
of death (mg/h)
N = 36 N = 17 0.86N = 24 N = 26 0.27
 Median (range)2.5(0.2–20)2.0(0.4–24) 3.0(0.2–20)2.0(0.4–10) 
 Mean (sd)3.5(3.7)4.0(5.7) 3.8(4.2)2.7(2.5)