Table 3 Independent prognostic indices of survival (Cox proportional hazards model)
Univariable analysis | Multivariable analysisa | |||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Advanced age (> 70 years) | 1.31 (1.09–1.58) | 0.004 | ||
Male sex | 1.21 (1.01–1.46) | 0.038 | 1.53 (1.15–2.04) | 0.004 |
Poor functional score (ECOG = 4) | 1.30 (1.08–1.57) | 0.005 | 1.45 (1.09–1.94) | 0.011 |
Lung cancer | 1.20 (0.96–1.50) | 0.108 | ||
Active infection | 1.06 (0.87–1.28) | 0.564 | ||
Leukocytosis | 1.56 (1.29–1.87) | < 0.001 | 1.98 (1.47–2.66) | < 0.001 |
Neutrophilia | 1.45 (1.19–1.75) | < 0.001 | ||
Lymphopenia | 1.53 (1.20–1.94) | 0.001 | ||
Anemia | 0.95 (0.71–1.26) | 0.711 | ||
Thrombocytopenia | 1.28 (1.04–1.59) | 0.022 | ||
Azotemia | 1.30 (1.06–1.61) | 0.013 | ||
Hypoalbuminemia | 1.88 (1.54–2.28) | < 0.001 | 2.06 (1.49–2.73) | < 0.001 |
Hyperbilirubinemia | 1.47 (1.21–1.80) | < 0.001 | ||
PT/INR prolongation | 1.46 (1.21–1.77) | < 0.001 | ||
CRP elevation | 1.28 (1.07–1.54) | 0.008 | ||
Hypokalemia | 1.01 (0.77–1.32) | 0.958 | ||
Hyperkalemia | 1.22 (1.01–1.48) | 0.044 | ||
Hyponatremia | 1.24 (1.03–1.49) | 0.025 | ||
Hypernatremia | 1.59 (1.22–2.07) | 0.001 | 1.55 (1.18–2.03) | 0.002 |