Table 3 Frequency and dose range of drugs prescribed in CSCI combinations recorded
Drug | UK Licensing status for SC Infusion | Frequency | Mean dose (mg) | Median dose (mg) | Dose range (mg) | IQR (mg) |
|---|---|---|---|---|---|---|
Midazolam hydrochloride | Unlicensed | 309 | 11.63 | 10 | (2.5, 60) | (5, 12.5) |
Oxycodone hydrochloride | Licensed | 230 | 21.09 | 15 | (2.5, 150) | (7.5, 25) |
Levomepromazine hydrochloride | Licensed | 225 | 13.77 | 6.25 | (6.2, 150) | (6.2, 12.5) |
Morphine sulphate | Unlicensed | 219 | 19.14 | 10 | (2.5, 190) | (7.5, 20) |
Glycopyrronium bromide | Unlicensed | 120 | 1.35 | 1.2 | (0.4, 2.4) | (0.6, 2) |
Hyoscine butylbromide | Unlicensed | 105 | 89.9 | 60 | (20, 240) | (60, 120) |
Alfentanil hydrochloride | Unlicensed | 82 | 1.8 | 1.12 | (0.2, 12.5) | (0.6, 2) |
Haloperidol lactate | Unlicensed | 66 | 2.7 | 2.5 | (0.5, 10) | (1.5, 3) |
Cyclizine lactate | Unlicensed | 62 | 150 | 150 | (150, 150) | (150, 150) |
Clonazepam | Unlicensed | 57 | 1.18 | 1 | (0.1, 6) | (0.2, 2) |
Metoclopramide hydrochloride | Unlicensed | 46 | 36.52 | 30 | (15, 90) | (30, 40) |
Ondansetron hydrochloride | Unlicensed | 33 | 15.52 | 12 | (8, 36) | (12, 16) |
Ketamine hydrochloride | Unlicensed | 13 | 171.15 | 150 | (100, 300) | (125, 200) |
Octreotide acetate | Unlicensed | 11 | 0.65 | 0.6 | (0.6, 0.9) | (0.6, 0.6) |
Hyoscine hydrobromide | Unlicensed | 11 | 1.47 | 1.2 | (1.2, 2.4) | (1.2, 1.5) |
Dexamethasone sodium phosphate | Unlicensed | 10 | 0.98 | 1 | (1, 1) | (1, 1) |
Levetiracetam | Unlicensed | 2 | 375 | 375 | (250, 500) | (312.5, 437.5) |
Furosemide | Unlicensed | 2 | 200 | 200 | (200, 200) | (200, 200) |
Diamorphine hydrochloride | Licensed | 2 | 7.5 | 7.5 | (5, 10) | (6.2, 8.8) |