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Table 3 Frequency and dose range of drugs prescribed in CSCI combinations recorded

From: An evaluation of continuous subcutaneous infusions across seven NHS acute hospitals: is there potential for 48-hour infusions?

Drug UK Licensing status for SC Infusion Frequency Mean dose (mg) Median dose (mg) Dose range (mg) IQR (mg)
Midazolam hydrochloride Unlicensed 309 11.63 10 (2.5, 60) (5, 12.5)
Oxycodone hydrochloride Licensed 230 21.09 15 (2.5, 150) (7.5, 25)
Levomepromazine hydrochloride Licensed 225 13.77 6.25 (6.2, 150) (6.2, 12.5)
Morphine sulphate Unlicensed 219 19.14 10 (2.5, 190) (7.5, 20)
Glycopyrronium bromide Unlicensed 120 1.35 1.2 (0.4, 2.4) (0.6, 2)
Hyoscine butylbromide Unlicensed 105 89.9 60 (20, 240) (60, 120)
Alfentanil hydrochloride Unlicensed 82 1.8 1.12 (0.2, 12.5) (0.6, 2)
Haloperidol lactate Unlicensed 66 2.7 2.5 (0.5, 10) (1.5, 3)
Cyclizine lactate Unlicensed 62 150 150 (150, 150) (150, 150)
Clonazepam Unlicensed 57 1.18 1 (0.1, 6) (0.2, 2)
Metoclopramide hydrochloride Unlicensed 46 36.52 30 (15, 90) (30, 40)
Ondansetron hydrochloride Unlicensed 33 15.52 12 (8, 36) (12, 16)
Ketamine hydrochloride Unlicensed 13 171.15 150 (100, 300) (125, 200)
Octreotide acetate Unlicensed 11 0.65 0.6 (0.6, 0.9) (0.6, 0.6)
Hyoscine hydrobromide Unlicensed 11 1.47 1.2 (1.2, 2.4) (1.2, 1.5)
Dexamethasone sodium phosphate Unlicensed 10 0.98 1 (1, 1) (1, 1)
Levetiracetam Unlicensed 2 375 375 (250, 500) (312.5, 437.5)
Furosemide Unlicensed 2 200 200 (200, 200) (200, 200)
Diamorphine hydrochloride Licensed 2 7.5 7.5 (5, 10) (6.2, 8.8)
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