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Table 3 Predictors of number of aggressive interventions received by patients in last month of life

From: A prospective cohort study assessing aggressive interventions at the end-of-life among patients with solid metastatic cancer

 

Univariable analysis1,2

Multivariable models1,3

Model 1

Model 2

Model 3

IRR [95% CI]

IRR [95% CI]

IRR [95% CI]

IRR [95% CI]

Physical health status before last month of life

0.99 [0.98, 1.01]

0.99 [0.98, 1.01]

  

Psychological health status before last month of life

1.00 [0.98, 1.01]

 

0.99 [0.98, 1.01]

 

Functional health status before last month of life

0.89* [0.83, 0.96]

  

0.88* [0.81, 0.95]

Length of hospital stay (in days)

1.01* [1.00, 1.01]

1.01* [1.01, 1.02]

1.01* [1.01, 1.02]

1.01* [1.01, 1.02]

Patient-reported palliative care use before last month of life

0.83 [0.66, 1.05]

0.91 [0.71, 1.16]

0.91 [0.70, 1.19]

1.06 [0.82, 1.36]

End of life care preference3

 Minimal life extension [Ref]

  Moderate life extension

0.96 [0.77, 1.21]

0.92 [0.72, 1.16]

0.88 [0.69, 1.12]

0.93 [0.74, 1.17]

  Aggressive life extension

0.87 [0.67, 1.13]

0.81 [0.62, 1.07]

0.79 [0.59, 1.04]

0.84 [0.64, 1.10]

  Age at death above median

0.87 [0.72, 1.05]

0.92 [0.73, 1.14]

0.91 [0.73, 1.15]

0.93 [0.75, 1.16]

  Male

1.16 [0.96, 1.41]

1.35* [1.06, 1.71]

1.34* [1.06, 1.70]

1.36* [1.08, 1.72]

Highest education

 Primary or lower [Ref]

  Secondary

1.06 [0.84, 1.33]

1.22 [0.95, 1.57]

1.23 [0.95, 1.59]

1.15 [0.90, 1.48]

  Above secondary

1.21 [0.95, 1.53]

1.30 [0.99, 1.71]

1.30 [0.98, 1.71]

1.24 [0.95, 1.63]

Religion

 Christian [Ref]

  Buddhist/ Taoist

1.37* [1.05, 1.78]

1.43* [1.09, 1.89]

1.41* [1.06, 1.89]

1.43* [1.08, 1.88]

  Muslim

1.13 [0.82, 1.57]

1.06 [0.75, 1.49]

1.10 [0.77, 1.56]

1.10 [0.78, 1.56]

  Hindu/ Sikh

1.22 [0.67, 2.19]

1.20 [0.66, 2.18]

1.19 [0.65, 2.19]

1.38 [0.75, 2.53]

  Free thinker/ No religion

0.93 [0.64, 1.35]

0.88 [0.59, 1.29]

0.87 [0.58, 1.31]

0.89 [0.60, 1.31]

Type of cancer

 Colorectal [Ref]

  Breast

1.34 [0.99, 1.81]

1.71* [1.19, 2.45]

1.64* [1.14, 2.37]

1.81* [1.27, 2.55]

  Respiratory

1.50* [1.16, 1.94]

1.67* [1.28, 2.18]

1.66* [1.27, 2.18]

1.68* [1.29, 2.19]

  Genitourinary/ Gynaecologic

1.17 [0.86, 1.58]

1.28 [0.94, 1.74]

1.25 [0.91, 1.71]

1.29 [0.95, 1.75]

  Others

1.23 [0.84, 1.81]

1.45 [0.97, 2.19]

1.32 [0.85, 2.05]

1.40 [0.94, 2.11]

  Number of months before death survey was answered

0.99 [0.93, 1.05]

1.00 [0.94, 1.06]

1.00 [0.94, 1.06]

0.98 [0.92, 1.05]

  1. 1Poisson regression; 2n = 298; 3n = 297; * Statistically significant at the 5% level