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Table 1 Patient demographics, N (%)

From: Methadone switching for refractory cancer pain

Demographics

All patients

N = 90

Unsuccessful switching

N = 26

Gender

  

Male

54 (60.0)

12 (46.2)

Female

36 (40.0)

14 (53.8)

Age (years), mean (SD)

53.4 (11.7)

56.7 (12.0)

≥ 60

33 (36.7)

13 (50.0)

Primary diagnosis

  

Lung cancer

35 (38.9)

11 (42.3)

Colorectal cancer

11 (12.2)

3 (11.5)

Cervical cancer

7 (7.8)

3 (11.5)

Gastric cancer

5 (5.6)

0 (0.0)

Breast cancer

4 (4.4)

1 (3.8)

Esophageal cancer

4 (4.4)

1 (3.8)

Others

24 (26.7)

7 (26.9)

Disease stage

  

Stage III

2 (2.2)

1 (3.8)

Stage IV

88 (97.8)

25 (96.2)

Karnofsky score

  

50

16 (17.8)

7 (26.9)

60

50 (55.6)

14 (53.8)

70

21 (23.3)

3 (11.5)

80

3 (3.3)

2 (7.7)

Bone metastasis

  

Yes

53 (58.9)

16 (61.5)

Pain type

  

Nociceptive pain

36 (40.0)

14 (53.8)

Neuropathic pain

20 (22.2)

5 (19.2)

Mixed pain

34 (37.8)

7 (26.9)

QTc, mean (SD)

0.35 (0.03)

0.35 (0.03)