Table 3 Conversion ratio from opioids to methadone
OMEDD pre-switching (mg) | Recommended initial CR | All N (%) | Initial CR Median (IQR) | Successful switching | Â | Failure switching | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Initial CR Median (IQR) | Under calculated ratio | Matched calculated ratio | Over calculated ratio | Â | N | Initial CR Median (IQR) | Less than calculated ratio | Equal to calculated ratio | More than calculated ratio | ||||
All | — | 90 | 7.3 (5.0–11.1) | 64 | 7.3 (5.4–10.6) | 39 (60.9) | 9 (14.1) | 16 (25.0) |  | 26 | 7.4 (4.0–14.2) | 14 (53.8) | 4 (15.4) | 8 (30.8) |
30–90 | 4:1 | 15 (16.7) | 3.3 (3.0–5.0) | 9 | 4.0 (3.2–5.5) | 4 (44.4) | 2 (22.2) | 3 (33.3) |  | 6 | 3.2 (2.8–4.5) | 4 (66.7) | 1 (16.7) | 1 (16.7) |
91–300 | 8:1 | 27 (30.0) | 6.0 (5.0–8.0) | 16 | 6.0 (5.3–8.0) | 10 (62.5) | 3 (18.8) | 3 (18.8) |  | 11 | 6.7 (4.7–8.3) | 6 (54.5) | 2 (18.2) | 3 (27.3) |
301–600 | 10:1 | 31 (34.4) | 8.0 (6.4–11.5) | 26 | 8.0 (6.3–10.1) | 17 (65.4) | 4 (15.4) | 5 (19.2) |  | 5 | 16.8 (8.0–21.6) | 2 (40.0) | 0 (0.0) | 3 (60.0) |
601–800 | 12:1 | 4 (4.4) | 9.2 (6.2–19.1) | 3 | 5.6, 10.4, 22.0 | 2 (66.7) | 0 (0.0) | 1 (33.3) |  | 1 | 8.0 | 1 (100.0) | 0 (0.0) | 0 (0.0) |
801–1000 | 15:1 | 3 (3.3) | 6.4, 10.7, 10.0 | 3 | 6.4, 10.7, 10.0 | 3 (100.0) | 0 (0.0) | 0 (0.0) |  | 0 | — | — | — | — |
> 1000 | 20:1 | 10 (11.1) | 22.4 (13.9–49.2) | 7 | 24.3 (14.7–65.2) | 3 (42.9) | 0 (0.0) | 4 (57.1) |  | 3 | 43.8, 20.4, 11.4 | 1 (33.3) | 1 (33.3) | 1 (33.3) |