Table 4 Adverse events pre- and post-switching to methadone, N (%)
Adverse events | Pre-switching | Post-switching | P value |
|---|---|---|---|
Constipation | 25 (27.8) | 21 (23.3) | 0.496 |
Nausea | 23 (25.6) | 21 (23.3) | 0.343 |
Vomiting | 15 (16.7) | 19 (21.1) | 0.447 |
Dizziness | 13 (14.4) | 14 (15.6) | 0.835 |
Decreased appetite | 12 (13.3) | 8 (8.9) | 0.343 |
Hidrosis | 6 (6.7) | 3 (3.3) | 0.347 |
Somnolence | 4 (4.4) | 3 (3.3) | 0.700 |
Urinary retention | 4 (4.4) | 0 (0.0) | 0.043 |
Delirium | 3 (3.3) | 7 (7.8) | 0.193 |
Pruritus | 2 (2.2) | 0 (0.0) | 0.155 |
Arrhythmia | 0 (0.0) | 1 (1.1) | 0.316 |
Respiratory depression | 0 (0.0) | 1 (1.1) | 0.316 |
Prostation | 0 (0.0) | 1 (1.1) | 0.316 |
Blurred vision | 0 (0.0) | 1 (1.1) | 0.316 |
Total | 51 (56.7) | 57 (63.3) | 0.447 |