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Table 3 Risk factors associated with depressive symptoms (DRS 3+) comparison of multiple imputation analyses models

From: Prevalence and risk factors of depressive symptoms in a Canadian palliative home care population: a cross-sectional study

Independent variable

Model with CHESSb(n = 5144) Pooled odds ratio (Pooled 95% confidence limit)

Model with Prognosis (n = 5144) Pooled odds ratios (Pooled 95% confidence limit)

Model with CHESSband prognostic awareness (n = 2547) Pooled odds ratios (Pooled 95% confidence limit)

Life satisfaction a

   

Low

3.01 (2.37-3.82)

2.58 (1.95-3.42)

3.62 (2.70-4.85)

High

Reference

Reference

Reference

CHESS b or Prognosis

   

- Imminent (days)

-

1.97 (1.32-2.94)

-

2+ - < 6 weeks

2.122 (1.42-3.18)

1.47 (1.13-1.91)

1.71 (1.05-2.80)g

0-1 -6 + weeks, < 6mths

Reference

Reference

Reference

Sleep disorders c

   

Severe

2.56 (2.05-3.19)

2.67 (2.03-3.52)

2.56 (1.93-3.39)

Moderate

1.56 (2.06-1.18)

1.82 (1.31-2.53)

1.35 (0.94-1.96)

Minimal

Reference

Reference

Reference

Pain scale

   

2+

1.73 (1.35-2.22)

1.69 (1.25-2.28)

2.09 (1.52-2.87)

0-1

Reference

Reference

Reference

Signs of caregiver distress

   

Yes

2.01 (1.62-2.51)

1.71 (1.29-2.26)

1.41 (1.08-1.85)

No

Reference

Reference

Reference

Gender

   

Female

1.37 (1.11-1.68)

1.47 (1.14-1.90)

1.41 (1.09-1.81)

Male

Reference

Reference

Reference

Cognitive impairment

   

CPSd 2+

1.45 (1.13-1.87)

1.71 (1.12-2.62)

1.39 (1.04-1.85)

0-1

Reference

Reference

Reference

Gastrointestinal symptoms

   

Moderate-Severe

1.27 (1.03-1.55)

1.37 (1.06-1.76)

N/Se

Minimal

Reference

Reference

 

# Co-morbidities

   

5+

N/Se

1.79 (1.24-2.59)

N/Se

3-4

 

1.17 (0.90-1.51)

 

0-2

 

Reference

 

Supportive family

   

No strong family support

N/Se

N/Se

1.99 (1.20-3.30)

Strong family support

  

Reference

Goodness of fit

   

C statistic (ROC curve)

0.77 (0.75-0.77)f

0.75 (0.74-0.76)f

0.76 (0.75-0.76)f

Hosmer & Lemeshow -χ 2

5.27(1.5-14.1)f

7.89 (2.2-16.9)f

9.25 (3.0-16.9)f

-p

0.73 (0.08-0.99)f

0.49 (0.03-0.98)f

0.37 (0.03-0.93)f

-df

8 (8-8)f

8 (8-8)f

8 (8-8)f

  1. a“High” life satisfaction indicates that the patient has all 5 of the following conditions present: a sense of completion, a sense of progress towards completion, acceptance of the situation, inner strengths that can be encouraged/nurtured AND a positive outlook. “Low” life satisfaction” indicates that one or more of the 5 conditions are absent in the patient.
  2. bCHESS = Changes in Health and End-Stage Disease Signs and Symptoms.
  3. c“Sleep disorders” is a composite (summative) measure based on two items: too little sleep (5 severity levels ranging from 0 to 4) and too much sleep (5 severity levels ranging from 0 to 4). “Severe” sleep disorders represent scores of 4+, “moderate” are scores of 2 or 3, and “minimal” are scores of 0 or 1.
  4. dCPS = Cognitive Performance Scale.
  5. eN/S = Not significant at alpha = 0.05 level.
  6. fMean (Minimum-Maximum).
  7. gAssumes a CHESS cutoff of 3+ versus <3 (to improve discriminatory power in this smaller sample focused on patients with prognosis < 6 months).