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Table 2 Patient characteristics and univariate survival analysis

From: Oxidative stress level is not associated with survival in terminally ill cancer patients: a preliminary study

 

No. of patients

MST (days)

HR (95% CI)

P Valueb

Age (years)

    

   ≤ 65

32

23

1

 

   > 65

33

11

1.19 (0.68-2.09)

0.544

Sex

    

   Female

31

31

1

 

   Male

34

11

1.95 (1.09-3.50)

0.024

Primary tumor site (any type)

    

   Lung

16

32

0.71 (0.37-1.36)

0.300

   Gastrointestinal

13

14

1.34 (0.68-2.66)

0.401

   Pancreas

11

17

1.38 (0.67-2.86)

0.387

   Hepatobiliary

10

10

1.39 (0.65-3.00)

0.396

   Others

15

19

0.70 (0.34-1.45)

0.332

ECOG PS

    

   2-3

44

23

1

 

   4

21

10

1.91 (1.06-3.45)

0.032

Palliative prognostic score

    

   < 7.5a

31

22

1

 

   ≥ 7.5a

34

10

2.30 (1.27-4.17)

< 0.01

Laboratory variables

    

   Bilirubin (mg/dL)

    

      WNR

47

22

1

 

      Hyperbilirubinemia

18

11

1.45 (0.79-2.69)

0.233

   Creatinine (mg/dL)

    

      WNR

56

22

1

 

      Elevated

9

6

4.22 (1.98-9.02)

< 0.01

   Lactate dehydrogenase (U/L)

    

      WNR

19

31

1

 

      Elevated

41

15

1.25 (0.65-2.42)

0.500

   Uric acid (mg/dL)

    

      WNR

54

22

1

 

      Hyperuricemia

8

12

2.10 (0.92-4.82)

0.078

   Albumin (g/dL)

    

      WNR

11

31

1

 

      Hypoalbuminemia

54

17

1.52 (0.68-3.39)

0.311

   C-reactive protein (mg/dL)

    

      < 16.3a

33

18

1

 

      ≥ 16.3a

32

19

0.60 (0.33-1.07)

0.084

   Serum vitamin C (μg/mL)

    

      ≥ 0.44a

33

17

1

 

      < 0.44a

32

20

0.71 (0.40-1.26)

0.240

   Oxidative stress (U.F.)

    

      < 412.9a

32

22

1

 

      ≥ 412.9a

33

15

1.15 (0.65-2.02)

0.637

  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group Performance Status, WNR within normal range, MST median survival time, HR hazard ratio, CI confidence interval.
  2. aMedian value.
  3. bGehan’s generalized Wilcoxon method.