Table 3 Oxidative stress status and baseline clinical characteristics

Aged (> 65 yrs)

1.06

0.40-2.82

0.914

Sex (male)

1.98

0.74-5.31

0.176

Palliative prognostic score (≥ 7.5^a)

1.20

0.45-3.18

0.714

Symptoms (presence)

    Fever

3.79

1.29-11.18

0.016

    Current infection

1.38

0.52-3.67

0.524

    Anorexia

0.48

0.08-2.84

0.421

    Dysphagia

2.13

0.76-2.97

0.151

    Dyspnea on exertion

1.63

0.50-5.25

0.417

    Uncontrolled pain (NRS ≥ 4)

1.75

0.66-4.69

0.263

Laboratory findings

    Hyperbilirubinemia

0.70

0.24-2.10

0.529

    Elevated creatinine

1.25

0.30-5.15

0.757

    Elevated lactate dehydrogenase

1.64

0.56-4.82

0.371

    Hyperuricemia

0.77

0.21-2.84

0.699

    Hypoalbuminemia

0.18

0.04-0.90

0.037

    High^a C-reactive protein

1.54

0.58-4.10

0.385

    Low^a vitamin C

0.74

0.28-1.95

0.537

Performance (ECOG = 4)

    Unadjusted

3.61

1.18-11.08

0.025

    Adjusted^b

4.45

1.14-17.33

0.031