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Table 4 BPI scores at baseline and end point (overall and by previous treatment)

From: An open-label, 1-year extension study of the long-term safety and efficacy of once-daily OROS® hydromorphone in patients with chronic cancer pain

 

Treatment in previous study

 

BPI variable

Mean (SD)

OROS®hydromorphone

(n = 35)

CR morphine

(n = 33)

Overall

(n = 68)

Pain at its worst1

   

   Baseline

4.3 (2.30)

5.1 (2.78)

4.7 (2.57)

   End point

5.9 (2.58)

5.8 (2.98)

5.9 (2.76)

Pain at its least1

   

   Baseline

1.3 (1.23)

1.8 (1.91)

1.6 (1.62)

   End point

2.2 (1.81)

2.4 (2.43)

2.3 (2.12)

Pain on average1

   

   Baseline

2.8 (1.89)

3.2 (2.10)

3.0 (2.00)

   End point

3.9 (2.30)

3.8 (2.50)

3.9 (2.38)

Current pain1

   

   Baseline

1.8 (1.84)

2.5 (2.21)

2.2 (2.05)

   End point

3.3 (2.86)

3.5 (2.49)

3.4 (2.67)

Pain relief2

   

   Baseline

74.4 (22.13)

70.0 (23.56)

72.2 (22.78)

   End point

61.5 (27.40)

58.2 (28.11)

59.8 (27.60)

  1. Baseline = absolute values; end point = last observation carried forward
  2. 10 = no pain, 10 = pain as bad as you can imagine; 20% to 100%
  3. BPI, brief pain inventory; CR, controlled-release; SD, standard deviation