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Table 5 Morphine equivalent daily dose by time in subjects with continuous exposure with cancer diagnosis

From: Dose patterns in commercially insured subjects chronically exposed to opioids: a large cohort study in the United States

Years Number of subjects Mean ± SD Median Min Max P25 P75 P95
Half year 177 65.29 ± 67.61 50.00 7.50 699.57 33.88 77.73 140.63
> 6 months to 1 year 148 86.63 ± 156.56 55.44 7.50 1702.50 30.00 89.10 240.00
> 1 to 1.5 years 79 71.96 ± 86.73 51.46 10.56 560.00 26.25 79.29 294.49
> 1.5 to 2 years 39 90.96 ± 92.61 60.00 15.00 431.88 30.00 98.12 347.94
> 2 to 2.5 years 19 99.55 ± 87.31 75.00 15.00 300.00 37.50 120.00 300.00
> 2.5 to 3 years 9 116.79 ± 95.72 105.00 15.00 318.12 45.00 139.74 318.12
> 3 to 3. 5 years 5 121.9 ± 130.19 45.00 15.00 298.74 27.50 223.27 298.74
> 3. 5 to 4 years 5 115.78 ± 125.49 45.00 15.00 295.71 23.82 199.38 295.71
> 4 to 4.5 years 5 151.37 ± 182.88 45.00 15.00 436.67 26.25 233.96 436.67
> 4.5 to 5 years 4 304.47 ± 422.07 141.43 15.00 920.00 30.00 578.93 920.00
> 5 to 5.5 years 3 394.28 ± 457.61 240.00 33.75 909.09 33.75 909.09 909.09
> 5.5 to 6 years 3 400.01 ± 471.87 233.78 33.75 932.50 33.75 932.50 932.50
> 6 to 6.5 years 3 315.39 ± 321.23 240.00 38.57 667.61 38.57 667.61 667.61
> 6.5 to 7 years 2 187.59 ± 209.35 187.59 39.55 335.62 39.55 335.62 335.62
> 7 to 7.5 years 1 381.73 ± . 381.73 381.73 381.73 381.73 381.73 381.73
> 7.5 to 8 years 0 - - - - - - -
> 8 years 0 - - - - - - -
  1. SD, standard deviation; P25, 25th percentile; P75; 75th percentile; P95; 95th percentile