Table 5 Morphine equivalent daily dose by time in subjects with continuous exposure with cancer diagnosis
Years | Number of subjects | Mean ± SD | Median | Min | Max | P25 | P75 | P95 |
|---|---|---|---|---|---|---|---|---|
Half year | 177 | 65.29 ± 67.61 | 50.00 | 7.50 | 699.57 | 33.88 | 77.73 | 140.63 |
> 6 months to 1 year | 148 | 86.63 ± 156.56 | 55.44 | 7.50 | 1702.50 | 30.00 | 89.10 | 240.00 |
> 1 to 1.5 years | 79 | 71.96 ± 86.73 | 51.46 | 10.56 | 560.00 | 26.25 | 79.29 | 294.49 |
> 1.5 to 2 years | 39 | 90.96 ± 92.61 | 60.00 | 15.00 | 431.88 | 30.00 | 98.12 | 347.94 |
> 2 to 2.5 years | 19 | 99.55 ± 87.31 | 75.00 | 15.00 | 300.00 | 37.50 | 120.00 | 300.00 |
> 2.5 to 3 years | 9 | 116.79 ± 95.72 | 105.00 | 15.00 | 318.12 | 45.00 | 139.74 | 318.12 |
> 3 to 3. 5 years | 5 | 121.9 ± 130.19 | 45.00 | 15.00 | 298.74 | 27.50 | 223.27 | 298.74 |
> 3. 5 to 4 years | 5 | 115.78 ± 125.49 | 45.00 | 15.00 | 295.71 | 23.82 | 199.38 | 295.71 |
> 4 to 4.5 years | 5 | 151.37 ± 182.88 | 45.00 | 15.00 | 436.67 | 26.25 | 233.96 | 436.67 |
> 4.5 to 5 years | 4 | 304.47 ± 422.07 | 141.43 | 15.00 | 920.00 | 30.00 | 578.93 | 920.00 |
> 5 to 5.5 years | 3 | 394.28 ± 457.61 | 240.00 | 33.75 | 909.09 | 33.75 | 909.09 | 909.09 |
> 5.5 to 6 years | 3 | 400.01 ± 471.87 | 233.78 | 33.75 | 932.50 | 33.75 | 932.50 | 932.50 |
> 6 to 6.5 years | 3 | 315.39 ± 321.23 | 240.00 | 38.57 | 667.61 | 38.57 | 667.61 | 667.61 |
> 6.5 to 7 years | 2 | 187.59 ± 209.35 | 187.59 | 39.55 | 335.62 | 39.55 | 335.62 | 335.62 |
> 7 to 7.5 years | 1 | 381.73 ± . | 381.73 | 381.73 | 381.73 | 381.73 | 381.73 | 381.73 |
> 7.5 to 8 years | 0 | - | - | - | - | - | - | - |
> 8 years | 0 | - | - | - | - | - | - | - |