Table 3 Subgroup analysis for survival based on the Glasgow Prognostic Score (GPS), and Charlson Comorbidity Index (CCI) within prognostic groups categorized by the Palliative Prognostic Index (PPI)
PPI | Subgroup by GPS or CCI | No. (%) | No. deaths (%) | Median survival, days (95% confidence interval) | Adjusted HR (95% confidence interval) | p |
|---|---|---|---|---|---|---|
Good prognosis (total score 0–4) | GPS score 0 | 4 (1.8) | 4 (100) | 70 (48.4–91.6) | 1 | 0.62 |
GPS score 1-2 | 48 (22.1) | 40 (83.3) | 49 (72.8–105.2) | 1.32 (0.44–3.97) | ||
CCI score 0 | 26 (12.0) | 18 (69.2) | 102 (49.5–154.5) | 1 | <0.001 | |
CCI score ≥ 1 | 26 (12.0) | 26 (100) | 41 (36.0–45.9) | 13.0 (4.7–35.9) | ||
Intermediate prognosis (total score 4.5–6) | GPS score 0 | 2 (0.9) | 2 (100) | 6 | 1 | 0.22 |
GPS score 1–2 | 31 (14.3) | 28 (90.3) | 16 (10.6–21.4) | 0.36 (0.07–1.88) | ||
CCI score 0 | 19 (8.8) | 17 (89.5) | 16 (0–31.6) | 1 | 0.80 | |
CCI score ≥1 | 14 (6.5) | 13 (92.9) | 10 (7.5–12.4) | 1.14 (0.40–3.26) | ||
Poor prognosis (total score >6) | GPS score 0 | 9 (4.1) | 8 (88.9) | 47 (0–152) | 1 | 0.013 |
GPS score 1–2 | 123 (56.7) | 122 (99.2) | 7 (4.7–9.3) | 2.66 (1.23–5.75) | ||
CCI score 0 | 69 (31.8) | 68 (98.6) | 7 (1.9–12.1) | 1 | 0.21 | |
CCI score ≥1 | 63 (29.0) | 62 (98.4) | 7 (4.1–9.9) | 0.72 (0.49–1.07) |