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Table 2 Relationships between the occurrence of pain flare and baseline variables (n = 135)

From: Incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: multicenter prospective observational study

  FLARE  
  NO YES  
  N (%) N (%) p-value*
Sex Male 55 (61.1 %) 35 (38.9 %) p = 0.706
Female 29 (64.4 %) 16 (35.6 %)
Cancer Site Lung 23 (54.8 %) 19 (45.2 %) p = 0.358
Prostate 16 (59.3 %) 11 (40.7 %)
Breast 15 (78.9 %) 4 (21.1 %)
Others 30 (63.8 %) 17 (36.2 %)
Bisphosphonates YES 23 (63.9 %) 13 (36.1 %) p = 0.810
NO 61 (61.6 %) 38 (38.4 %)
RT Dose 8 Gy/ 1 fx 28 (66.7 %) 14 (33.3 %) p = 0.091
20 Gy / 5 fx 47 (56.6 %) 36 (43.4 %)
Other 9 (90.0 %) 1 (10.0 %)
Dexamethasone during RT YES 25 (56.1 %) 18 (43.9 %) p = 0.379
NO 59 (64.1 %) 33 (35.9 %)
  1. Abbreviations: RT: radiotherapy; Fx: fraction
  2. *p-value: chi-square/Fisher exact test