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Table 4 The correlation coefficients between total morphine dose and morphine concentration, and its metabolites in serum and urine (n = 24)

From: Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: an observational study

 

M

M6G

M3G

Serum (Day1)

0.53 (0.01)

0.58 (0.00)

0.72 (<0.01)

Urine (Day1)

0.44 (0.03)

0.68 (<0.01)

0.65 (<0.01)

Urine (Day2)

0.47 (0.02)

0.46 (0.02)

0.51 (0.01)

Urine (Day3)

0.55 (0.01)

0.76 (<0.01)

0.65 (<0.01)

  1. M Morphine, M6G Morphine-6-glucuronide, M3G Morphine-3-glucuronide
  2. P-values are parenthesized and derived from spearman rank correlation