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Table 1 Level of evidence for interventions

From: Paediatric palliative care: recommendations for treatment of symptoms in the Netherlands

Level of evidence

Evidence is based on:

Level 1

Systematic review or at least two randomized clinical trials of good quality

Level 2

One randomized clinical trial or at least two case–control studies

Level 3

One case–control study or one cohort study

Level 4

Textbook or expert opinion