Table 4 EORTC QLQ-C30 mean values at baseline and follow-up assessment of response rate and progression free survival-ratio according to RECIST (PR = partial remission, SD = stable disease, PD = progressive disease, PFS = progression free survival ratio)
| Â | Response | PFS | ||||
|---|---|---|---|---|---|---|
| Â | RECIST | Baseline | Follow-up | Ratio | Baseline | Follow-up |
QoL/GHS (Quality of Life/Global Health Status) | PR | 53.65 | 57.81 | >1 | 59.17 | 56.85 |
SD | 53.03 | 55.00 | Â | Â | Â | |
PD | 41.67 | 36.11 | <1 | 36.76 | 49.24 | |
PF (Physical Functioning) | PR | 65.00 | 70.83 | >1 | 68.22 | 69.20 |
SD | 70.91 | 67.30 | Â | Â | Â | |
PD | 57.04 | 48.89 | <1 | 62.75 | 62.42 | |
RF (Role Functioning) | PR | 57.29 | 48.96 | >1 | 57.78 | 55.75 |
SD | 57.58 | 54.76 | Â | Â | Â | |
PD | 37.04 | 22.22 | <1 | 46.08 | 34.85 | |
EF (Emotional Functioning) | PR | 70.31 | 68.23 | >1 | 65.00 | 66.96 |
SD | 59.85 | 63.33 | Â | Â | Â | |
PD | 43.52 | 55.56 | <1 | 51.96 | 59.09 | |
CF (Cognitive Functioning) | PR | 87.50 | 81.25 | >1 | 88.33 | 83.33 |
SD | 88.64 | 83.33 | Â | Â | Â | |
PD | 68.52 | 72.22 | <1 | 77.45 | 77.27 | |
SF (Social Functioning) | PR | 39.58 | 51.04 | >1 | 52.77 | 57.14 |
SD | 56.06 | 64.17 | Â | Â | Â | |
PD | 31.48 | 22.22 | <1 | 33.33 | 51.52 | |
FA (Fatigue, Symptom Score) | PR | 37.50 | 47.22 | >1 | 44.44 | 43.68 |
SD | 50.00 | 41.27 | Â | Â | Â | |
PD | 62.96 | 74.07 | <1 | 54.90 | 52.52 | |
NV (Nausea and Vomiting, Symptom Score) | PR | 17.71 | 13.54 | >1 | 16.67 | 14,94 |
SD | 16.67 | 15.08 | Â | Â | Â | |
PD | 16.67 | 5.56 | <1 | 17.65 | 10.61 | |
PAIN (Symptom Score) | PR | 29.17 | 30.21 | >1 | 26.67 | 21.83 |
SD | 21.97 | 15,87 | Â | Â | Â | |
PD | 35.19 | 50.00 | <1 | 27.45 | 30,30 | |
DYS (Dyspnoe, Symptom Score) | PR | 20.83 | 31.25 | >1 | 33.33 | 37.93 |
SD | 39.39 | 44.44 | Â | Â | Â | |
PD | 51.85 | 55.56 | <1 | 39.22 | 45.45 | |
INS (Insomnia, Symptom Score) | PR | 27.08 | 22.92 | >1 | 37.78 | 28.74 |
SD | 50.00 | 39.68 | Â | Â | Â | |
PD | 33.33 | 44.44 | <1 | 41.18 | 45.45 | |
AL (Appetite Loss, Symptom Score) | PR | 31.25 | 33.33 | >1 | 32.22 | 34.48 |
SD | 31.82 | 28.57 | Â | Â | Â | |
PD | 62.96 | 44.44 | <1 | 47.06 | 24.24 | |
CON (Constipation, Symptom Score) | PR | 14.58 | 6.25 | >1 | 14.44 | 9.52 |
SD | 9.09 | 11.67 | Â | Â | Â | |
PD | 12.50 | 0.00 | <1 | 6.25 | 6.06 | |
DIA (Diarrhoea, Symptom Score) | PR | 18.75 | 27.08 | >1 | 28.89 | 29.76 |
SD | 27.27 | 26.67 | Â | Â | Â | |
PD | 29.63 | 33.33 | <1 | 17.65 | 21.21 | |
FIN (Financial Difficulties, Symptom Score) | PR | 29.17 | 27.03 | >1 | 22,22 | 27.16 |
SD | 24.24 | 35.09 | Â | Â | Â | |
PD | 18.52 | 0.00 | <1 | 29.41 | 33.33 | |