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Table 3 Factors associated with four domains (PCS, MCS, VT, and RE) of the SF-12 of the patients by multiple linear regressions

From: Factors influencing the health-related quality of life of Chinese advanced cancer patients and their spousal caregivers: a cross-sectional study

Independent variables

PCS_P

MCS_P

VT_P

RE-P

Coef B (95 % CI)

P-value

Coef B (95 % CI)

P-value

Coef B (95 % CI)

P-value

Coef B (95 % CI)

P-value

Constant

44.32(33.47,55.17)

0.000

37.39(29.55,45.23)

0.000

34.68(25.01,44.34)

0.000

32.80(21.80,43.80)

0.000

3a: Patients’ characteristics

        

 Male vs. Female_Pa

2.18(−1.23,5.60)

0.207

−0.56(−3.019,1.91)

0.656

3.40(0.36,6.44)

0.029

−1.98(−5.44,1.48)

0.259

 Time since diagnosis of cancer

−0.02(−0.09,0.05)

0.533

−0.05(−0.10,0.004)

0.074

−0.07(−0.14,−0.01)

0.020

−0.05(−0.12,0.02)

0.142

 Partly vs. Well informed

−1.10(−4.87,2.67)

0.565

−1.95(−4.67,0.78)

0.160

0.35(−3.01,3.70)

0.839

−3.02(−6.84,0.80)

0.120

3b: Spousal caregivers’ characteristics

       

 Level of education (vs. University or above)

       

  Primary school

1.06(−4.46,6.57)

0.705

4.79(0.80,8.77)

0.019

3.30(−1.62,8.21)

0.186

8.71(3.12,14.30)

0.003

  High school

0.26(−5.14,5.66)

0.925

2.61(−1.29,6.51)

0.187

1.47(−3.34,6.28)

0.546

5.86(0.38,11.33)

0.036

 Working vs. Non working

0.83(−2.41,4.07)

0.612

0.93(−1.42,3.27)

0.435

3.28(0.40,6.17)

0.026

0.81(−2.48,4.10)

0.626

 Partly vs. Well informed

2.09(−2.18,6.37)

0.334

2.20(−0.89,5.29)

0.161

4.36(0.55, 8.17)

0.025

4.67(0.33, 9.00)

0.035

 Time spent in caring for P/day

−0.87(−2.12,0.38)

0.172

0.03(−0.87,0.94)

0.945

−0.02(−1.14,1.09)

0.969

−0.44(−1.71,0.83)

0.491

3c: Dyads’ characteristics

        

 Change in the relationship with their partner after the diagnosis of cancer

      

  Improved vs. No change

−0.53(−4.06,2.99)

0.765

−0.91(−3.46,1.64)

0.481

2.90(−0.24,6.04)

0.070

−3.81(−7.39,−0.24)

0.037

 Financial burden on the family due to the treatment of cancer (vs. Mild or None)

     

  Serious

−6.23(−14.87,2.42)

0.157

1.20(−5.05,7.45)

0.704

2.77(−4.30,10.48)

0.477

−1.84(−10.61,6.93)

0.678

  Normal

−4.63(−13.39,4.14)

0.298

2.98(−3.36,9.31)

0.354

4.60(−3.21,12.41)

0.245

1.76(−7.13,10.65)

0.696

3d: HADS

        

 PCFAC: HAD of patients

−3.00(−4.90,−1.10)

0.002

−2.40(−3.77,-1.03)

0.001

−2.49(−4.18,−0.80)

0.004

−3.54(−5.47,−1.61)

0.000

 PCFAC: HAD of SC

−0.51(−2.39,1.37)

0.594

−0.80(−2.16,0.56)

0.248

−0.37(−2.05,1.31)

0.662

−1.53(−3.44,0.38)

0.115

  1. PCS physical component summary, MCS mental component summary, VT vitality, RE role emotional, P patient, SC spousal caregivers; Coef B unstandardized regression coefficient B; CI confidence interval, PCFAC: HAD principal component from factor analysis of anxiety and depression
  2. aThe findings in the gender analysis of the patients are the opposite of those in the gender analysis of spousal caregivers