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Table 3 Factors associated with four domains (PCS, MCS, VT, and RE) of the SF-12 of the patients by multiple linear regressions

From: Factors influencing the health-related quality of life of Chinese advanced cancer patients and their spousal caregivers: a cross-sectional study

Independent variables PCS_P MCS_P VT_P RE-P
Coef B (95 % CI) P-value Coef B (95 % CI) P-value Coef B (95 % CI) P-value Coef B (95 % CI) P-value
Constant 44.32(33.47,55.17) 0.000 37.39(29.55,45.23) 0.000 34.68(25.01,44.34) 0.000 32.80(21.80,43.80) 0.000
3a: Patients’ characteristics         
 Male vs. Female_Pa 2.18(−1.23,5.60) 0.207 −0.56(−3.019,1.91) 0.656 3.40(0.36,6.44) 0.029 −1.98(−5.44,1.48) 0.259
 Time since diagnosis of cancer −0.02(−0.09,0.05) 0.533 −0.05(−0.10,0.004) 0.074 −0.07(−0.14,−0.01) 0.020 −0.05(−0.12,0.02) 0.142
 Partly vs. Well informed −1.10(−4.87,2.67) 0.565 −1.95(−4.67,0.78) 0.160 0.35(−3.01,3.70) 0.839 −3.02(−6.84,0.80) 0.120
3b: Spousal caregivers’ characteristics        
 Level of education (vs. University or above)        
  Primary school 1.06(−4.46,6.57) 0.705 4.79(0.80,8.77) 0.019 3.30(−1.62,8.21) 0.186 8.71(3.12,14.30) 0.003
  High school 0.26(−5.14,5.66) 0.925 2.61(−1.29,6.51) 0.187 1.47(−3.34,6.28) 0.546 5.86(0.38,11.33) 0.036
 Working vs. Non working 0.83(−2.41,4.07) 0.612 0.93(−1.42,3.27) 0.435 3.28(0.40,6.17) 0.026 0.81(−2.48,4.10) 0.626
 Partly vs. Well informed 2.09(−2.18,6.37) 0.334 2.20(−0.89,5.29) 0.161 4.36(0.55, 8.17) 0.025 4.67(0.33, 9.00) 0.035
 Time spent in caring for P/day −0.87(−2.12,0.38) 0.172 0.03(−0.87,0.94) 0.945 −0.02(−1.14,1.09) 0.969 −0.44(−1.71,0.83) 0.491
3c: Dyads’ characteristics         
 Change in the relationship with their partner after the diagnosis of cancer       
  Improved vs. No change −0.53(−4.06,2.99) 0.765 −0.91(−3.46,1.64) 0.481 2.90(−0.24,6.04) 0.070 −3.81(−7.39,−0.24) 0.037
 Financial burden on the family due to the treatment of cancer (vs. Mild or None)      
  Serious −6.23(−14.87,2.42) 0.157 1.20(−5.05,7.45) 0.704 2.77(−4.30,10.48) 0.477 −1.84(−10.61,6.93) 0.678
  Normal −4.63(−13.39,4.14) 0.298 2.98(−3.36,9.31) 0.354 4.60(−3.21,12.41) 0.245 1.76(−7.13,10.65) 0.696
3d: HADS         
 PCFAC: HAD of patients −3.00(−4.90,−1.10) 0.002 −2.40(−3.77,-1.03) 0.001 −2.49(−4.18,−0.80) 0.004 −3.54(−5.47,−1.61) 0.000
 PCFAC: HAD of SC −0.51(−2.39,1.37) 0.594 −0.80(−2.16,0.56) 0.248 −0.37(−2.05,1.31) 0.662 −1.53(−3.44,0.38) 0.115
  1. PCS physical component summary, MCS mental component summary, VT vitality, RE role emotional, P patient, SC spousal caregivers; Coef B unstandardized regression coefficient B; CI confidence interval, PCFAC: HAD principal component from factor analysis of anxiety and depression
  2. aThe findings in the gender analysis of the patients are the opposite of those in the gender analysis of spousal caregivers