Table 1 Demographic characteristics
Cohort 1 (n = 77) | Cohort 2 (n = 116) | p value | |
|---|---|---|---|
Gestational age, mean (+/− SD) (weeks) | 30 (5) | 29 (5.1) | 0.451 |
Weight, mean (+/− SD) (g) | 1508 (1056) | 1435 (994) | 0.666 |
Sex, n (%) | |||
Female | 36 (46.8) | 50 (43.1) | 0.617 |
Place of birth, n (%) | |||
Inborn | 56 (72.7) | 64 (55.2) | 0.014 |
Resuscitation in delivery room, n (%) | |||
Yes | 63 (81.8) | 89 (76.7) | 0.397 |
Apgar < 7 to 5 min, n (%) | 34 (44.1) | 60 (51.7) | 0.853 |
Birth context, n (%) | |||
Perinatal asphyxia | 8 (10.4) | 12 (10.3) | 0.674 |
Congenital anomaly | 14 (18.2) | 13 (11.2) | |
Premature | 17 (22.1) | 25 (21.6) | |
Weight < 1000 g | 37 (48.1) | 63 (54.3) | |
Other | 1 (1.3) | 3 (2.6) | |
Age at death, mean (+/− SD) (days) | 19 (51) | 15 (21) | 0.525 |
Age at death, median (IQR) (days) | 6 (16) | 7 (16) | |
Death delay time, n (%) | |||
Within 48 h | 21 (27.3) | 21 (18.1) | 0.131 |
In the first week | 22 (28.6) | 42 (36.2) | 0.270 |
Within three weeks | 20 (26) | 29 (25) | 0.879 |
Within two months | 7 (9.1) | 17 (14.7) | 0.251 |
Within three months | 4 (5.2) | 3 (2.6) | 0.343 |
Antenatal palliative care decision, n (%) | 1 (1.3) | 0 | 0.218 |
Verhagen classification, n (%) | |||
Class 1 | 12 (15.6) | 15 (12.9) | 0.061 |
Class 2 | 35 (45.5) | 34 (29.3) | |
Class3 | 10 (13) | 16 (13.2) | |
Class 4 | 20 (26) | 50 (43.1) | |
Cause of death, n (%) | |||
Severe hypoxic-ischemic encephalopathy | 9 (11.7) | 13 (11.2) | 0.708 |
Other neurological injury | 16 (20.8) | 35 (30.2) | |
Sepsis | 16 (20.8) | 17 (14.7) | |
Hemodynamic failure | 19 (24.7) | 29 (25) | |
Congenital anomaly | 7 (9.1) | 10 (8.6) | |
Respiratory failure | 10 (13) | 11 (9.5) | |
Other | 0 | 1 (0.9) | |
Collaborative decision meeting, n (%) | 25 (32.5) | 64 (55.2) | 0.002 |