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Table 2 Men with metastatic prostate cancer’s ratings of their QoL, functioning and symptoms (mean, SD, proportions) in relation to clinically relevant threshold values, as well as comparisons between groups based on time from last questionnaire to death p-values from One way ANOVA

From: Quality of life in men with metastatic prostate cancer in their final years before death – a retrospective analysis of prospective data

Variable Threshold valuesd Total score < 6 months before death 6–18 months before death > 18 months before death P-value1
Mean (SD) n Prop.e (%) Mean (SD) n Prop.e (%) Mean (SD) n Prop.e(%) Mean (SD) n Prop.e (%)  
Global health/QoLa 70 56.0 (26.7) 189 70.1 38.5 (27.3) 40 87.5 55.7 (23.5) 64 75.0 64.5 (24.9) 85 59.3 < 0.001
Social functioninga   66.8 (29.3) 187   50.4 (32.5) 38   66.4 (27.2) 63   74.4 (26.4) 86   < 0.001
Emotional functioninga 70 72.9 (23.4) 188 43.6 59.5 (28.3) 39 67.5 73.6 (19.5) 63 46.9 78.5 (21.4) 86 29.0 < 0.001
Cognitive functioninga   78.4 (22.8) 190   67.9 (27.1) 40   78.4 (22.7) 64   83.3 (19.0) 86   0.002
Physical functioninga 83 72.9 (28.6) 187 54.5 54.2 (31.8) 38 75.0 71.7 (28.5) 64 56.3 82.2 (22.7) 85 42.4 < 0.001
Role functioninga   60.2 (36.7) 173   36.7 (35.0) 34   57.4 (39.4) 61   72.6 (29.5) 78   < 0.001
Fatigueb 39 39.2 (29.1) 189 38.6 62.1 (29.7) 39 70.0 39.9 (28.3) 64 40.6 28.2. (22.8) 86 22.1 < 0.001
Painb 25 31.8 (32.1) 190 49.5 53.8 (34.5) 40 77.5 29.4 (29.5) 64 50.0 23.3 (28.3) 86 36.0 < 0.001
Nausea /vomitb   10.6 (17.3) 190   23.8 (23.2) 40   8.6 (15.4) 64   6.0 (11.7) 86   < 0.001
Dyspnoeab   32.5 (29.5) 189   49.6 (34.9) 39   32.3 (27.2) 64   24.8 (25.1) 86   < 0.001
Insomniab   27.5 (28.7) 189   35.0 (29.2) 40   29.2 (29.4) 64   22.7 (27.3) 85   0.071
Constipationb   17.8 (28.7) 187   34.2 (38.1) 40   14.3 (24.5) 63   12.7 (23.7) 84   0.001
Appetite lossb   17.9 (27.4) 190   42.5 (32.9) 40   14.6 (24.4) 64   8.9 (18.7) 86   < 0.001
Diarrhoeab   15.0 (24.2) 187   18.8 (27.4) 39   10.6 (20.6) 63   16.5 (25.0) 85   0.186
Urinary problemsc   2.8 (3.1) 184   3.7 (3.2) 38   2.4 (3.1) 63   2.6 (3.0) 83   0.082
Bowel problemsc   2.7 (2.7) 182   3.7 (2.9) 38   2.8 (2.8) 62   2.2 (2.5) 82   0.027
Sexual problemsc   6.9 (4.2) 173   7.0 (4.5) 36   7.5 (3.8) 58   6.3 (4.2) 79   0.219
  1. 1Tested with One-way ANOVA
  2. aEORTC-QLQ-C30. Higher values indicate better QoL and functioning
  3. bEORTC-QLQ-C30. Higher values indicate more symptoms
  4. cPCSS. Higher values indicate more problems
  5. dValues that indicate the need for clinical attention
  6. eProportion of values over/under the threshold values