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Table 2 Aggressiveness of care in the last 30 days of life for 278 patients with pancreatic cancer

From: Timing of palliative care referral and aggressive cancer care toward the end-of-life in pancreatic cancer: a retrospective, single-center observational study

 

Palliative Care Referral (Days Before Death)

 

Early (> 90 days)

Late (≤ 90 days)

p-value

N = 91

N = 187

Emergency Department (ED) Presentations

No of ED presentations

 Total number of patients

22 (24.2%)

79 (42.2%)

0.003

 No of patients presenting once

19 (86.3%)

67 (84.8%)

0.57a

 No of patients presenting twice

2 (9.1%)

11 (13.9%)

 

 No of patients presenting thrice

1 (4.6%)

1 (1.3%)

 

 Total number of presentations

26

92

 

Reason for ED presentation (based upon all presentations in last 30 days of life)b

 Pain

9 (34.6%)

19 (20.7%)

 

 Nausea/Vomiting

1 (3.8%)

16 (17.4%)

 

 Confusion

1 (3.8%)

8 (8.7%)

 

 Other Symptoms

7 (26.9%)

8 (8.7%)

 

 Infection

3 (11.5%)

8 (8.7%)

 

 Complications of Cancer

6 (23.1%)

22 (23.9%)

 

 Investigations and Procedures

0

1 (1.1%)

 

 Funtional decline

0

4 (4.3%)

 

 Other medical problems

0

9 (9.8%)

 

 End of life care

1 (3.8%)

0

 

Outcome of ED presentation

 Admit to acute hospital

18 (81.8%)

66 (83.6%)

0.26

 Discharge home from ED

1 (4.6%)

8 (10.1%)

 

 Transfer to palliative care unit

0

2 (2.5%)

 

 Death in ED

3 (13.6%)

3 (3.8%)

 

Acute Hospital Admissions by Patient

No of acute hospital admission

 Total number of patients

48 (52.8%)

122 (65.2%)

0.04

 0

43 (47.3%)

65 (34.7%)

0.009

 1

47 (51.6%)

104 (55.6%)

 

 2

1 (1.1%)

16 (8.6%)

 

 3

0

2 (1.1%)

 

 Total admission episodes

49

142

 

Outcome of acute hospital admission (total admission episodes)

 Discharge home from ward

12 (24.5%)

48 (33.8%)

0.31

 Transfer to palliative care unit

19 (38.8%)

55 (38.7%)

 

 Transfer to another hospital

0

2 (1.4%)

 

 Death on ward

18 (36.7%)

37 (26.1%)

 

Intensive Care Admission

1 (1.1%)

2 (1.1%)

0.98

Chemotherapy Use

Received any chemotherapyc

73 (80.2%)

97 (51.9%)

< 0.001

Received Chemotherapy < 30 daysd

12/72 (16.7%)

23/94 (24.5%)

0.22

  1. Data presented as number (%)
  2. aTesting hypothesis of a difference in number of presentations, in patients who present to ED.
  3. bPatients may present with ≥1 reason to ED
  4. cFigures relate to any chemotherapy, not just < 30 days
  5. dExcludes 4 patients with unknown chemotherapy status