Table 4 characteristics of included studies

Abernethy, A [25]

28/239 (11.7%)

8/120 (6.7%)

20/119 (16.8%)

Abernethy, A [26]

314/461 (68.1%)

69%

65.90%

Ahmedzai, S [27]

51/184 (27.7%)

26/92 (28.3%)

25/92 (27.2%)

Ando, M [28]

9/77 (11.7%)

4/38 (10.5%)

5/39 (12.8%)

Aoun, S [29]

15/58 (25.9%)

12/38 (31.6%)

3/20 (15%)

Barton, R [30]

11/22 (50%)

5/11 (45.5%)

6/11 (54.5%)

Bausewein, C [31]

34/70 (48.6%)

14/38 (36.8%)

20/32 (62.5%)

Beijer, S [32]

43/100 (43%)

22/51 (43.1%)

21/49 (42.9%)

Bennett, M [33]

5/24 (20.8%)

2/12 (16.7%)

3/12 (25%)

Bhatnagar, S [34]

NA

NA

NA

Brännström, M [35]

12/72 (16.7%)

NA

NA

Breitbart, W [36]

52/90 (57.8%)

24/49 (49%)

28/41 (68.3%)

Breitbart, W [37]

53/120 (44.2%)

31/64 (48.4%)

22/56 (39.2%)

Brisbois, T [38]

25/46 (54.3%)

13/24 (54.2%)

12/22 (54.5%)

Bruera, E [39]

49/190 (25.8%)

36/142 (25.4%)

13/48 (27.1%)

Bruera, E [40]

27/129 (20.9%)

14/63 (22.2%)

13/66 (19.7%)

Chan, C [41]

27%

11%

42%

Chen, H [42]

32/90 (35.6%)

14/45 (31.1%)

18/45 (40%)

Cheville, A [43]

10/66 (15.2%)

7/33 (21.2%)

3/33 (9.1%)

Chochinov, H M [44]

115/441 (26.1%)

57/165 (34.5%)

58/276 (21%)

Chow, E [45]

298/819 (36.4%)

148/406 (36.5%)

150/413 (36.3%)

Cruciani, R [46]

167/376 (44.4%)

85/189 (45%)

82/187 (43.9%)

De Raaf, P [47]

60/152 (38.2%)

40/76 (52.6%)

20/76 (26.3%)

Del Fabbro, E [48]

14/43 (32.6%)

6/19 (31.6%)

8/24 (33.3%)

Donovan, H [49]

17/65 (26.2%)

16/33 (48.5%)

1/32 (3.1%)

Edmonds, P [50]

6/52 (11.5%)

1/26 (3.8%)

5/26 (19.2%)

El-Jawahri, A [51]

0/50

0/23

0/27

Epstein, A [52]

2/56 (3.6%)

1/30 (3.3%)

1/26 (3.8%)

Farquhar, M [53]

20/67 (29.9%)

12/35 (34.3%)

8/32 (25%)

Fischer, S [54]

30/64 (46.9%)

14/32 (43.75%)

16/32 (50%)

Galbraith, S [55]

NA

NA

NA

Galfin,J [56]

9/34 (26.5%)

6/19 (31.6%)

3/15 (20%)

Gebbia, V [57]

10/86 (11.6%)

5/42 (11.9%)

5/39 (12.8%)

Greer, J [58]

12/40 (30%)

6/20 (30%)

6/30 (30%)

Gutgsell, K [59]

2/200 (1%)

1/100 (1%)

1/100 (1%)

Hardy,J [60]

113/187 (60.4%)

54/93 (58.1%)

57/92 (62%)

Heisler, M [61]

32/160 (20%)

16/84 (19%)

16/76 (21.1%)

Henke, C [62]

15/44 (34.1%)

6/24 (25%)

9/20 (45%)

Herr, K [63]

NA

NA

NA

Homsi, J [64]

5/37 (13.5%)

NA

NA

Hopkinson, J [65]

15/65 (23.1%)

10/35 (28.6%)

5/30 (16.7%)

Hui, D [66]

0/20

0/10

0/10

Hui, D [67]

7/30 (73.3%)

2/15 (13.3%)

5/15 (33.3%)

Ishiki, H [68]

6/27 (22.2%)

NA

NA

Israel, F [69]

9/31 (29%)

1/11 (9.1%)

8/20 (40%)

Johnson, J [70]

33/177 (18.6%)

25/118 (21.2%)

8/59 (13.6%)

Jones, L [71]

9/77 (11.7%)

3/42 (7.1%)

6/35 (17.1%)

Jones, L [72]

5/41 (12.2%)

1/21 (4.8%)

4/20 (20%)

Julião, M [73]

44/80 (55%)

22/39 (56.4%)

22/41 (53.7%)

Kerr, C [74]

4/34 (11.8%)

2/17 (11.8%)

2/17 (11.8%)

Kirste, S [75]

10/44 (22.7%)

7/22 (31.8%)

3/22 (13.6%)

Lee, C [76]

3/9 (33.3%)

2/4 (50%)

1/5 (20%)

Liao, J [77]

14/160 (8.75%)

9/66 (13.6%)

5/94 (5.3%)

Lim, J [78]

NA

NA

NA

Lloyd-Williams, M [79]

44/100 (44%)

24/49 (49%)

20/51 (39.2%)

López-Sendín, N [80]

9/24 (37.5%)

4/12 (33.3%)

5/12 (41.7%)

Lundholm, K [81]

9/31 (29%)

5/17 (29.4%)

4/14 (28.6%)

McLean, L [82]

6/42 (14.3%)

4/22 (18.2%)

2/20 (10%)

Mok, E [83]

26/84 (31%)

15/44 (34.1%)

11/40 (27.5%)

Ng, C [84]

49/88 (55.7%)

23/44 (52.3%)

26/44 (59.1%)

Oldervoll, L [85]

68/231 (29.4%)

43/121 (35.5%)

25/110 (22.7%)

Oxberry, S [86]

4/39 (10.3%)

NA

NA

Pantilat, S [87]

26/107 (24.2%)

13/54 (24.1%)

13/53 (24.5%)

Pelayo-Alvarez, M [88]

7/124 (5.6%)

3/66 (4.5%)

4/58 (6.9%)

Popa-Velea, O [89]

NA

NA

NA

Portenoy, R [90]

97/360 (26.9%)

72/269 (26.8%)

25/91 (27.5%)

Rhondali, W [91]

2/80 (2.5%)

NA

NA

Ringash, J [92]

NA

41%

53%

Salas, S [93]

0/20

0/11

0/9

Schofield, P [94]

29/108 (26.9%)

17/55 (30.9%)

12/53 (22.6%)

Sidebottom, A [95]

33/232 (14.2%)

23/116 (19.8%)

10/116 (8.6%)

Stein, R [96]

58/120 (48.3%)

24/55 (43.6%)

34/65 (52.3%)

Sternberg, C [97]

NA

NA

NA

Suh, S [98]

3/41 (7.3%)

2/20 (10%)

1/21 (4.8%)

Temel, J [99]

115/151 (76.2%)

NA

NA

Uitdehaag, M [100]

7/21 (33.3%)

3/11 (27.3%)

4/10 (40%)

Uitdehaag, M [101]

133/138 (96.4%)

67/70 (95.7%)

66/68 (97.1%)

Vogel, R [102]

6/35 (17.1%)

4/20 (20%)

2/15 (13.3%)

Volandes, A [103]

83/150 (55.3%)

40/70 (57.1%)

43/80 (53.75%)

Wallen, G [104]

102/152 (67.1%)

54/76 (71.1%)

48/76 (63.2%)

Wentlandt, K [105]

18/451 (4%)

NA

NA

Wyatt, G [106]

NA

NA

NA

Zaghloul, M [107]

11/40 (27.5%)

3/20 (15%)

8/20 (40%)

Zimmermann, C [108]

175/461 (38%)

97/228 (42.5%)

78/233 (33.5%)

Laltanpui, C [109]

NA

NA

NA

Litterini, A [110]

52/66 (78.8%)

23/34 (67.7%)

29/32 (90.6%)

Mariani, P [111]

13/80 (16%)

8/ 43 (18.6%)

5/37 (13.5%)

Ng, C [112]

0/60

0/30

0/30

Strong, R [113]

0/11

NA

NA

Vermandere, M [114]

6/55 (11%)

3/28 (10.7%)

3/27 (11%)

Agrwal, K [115]

5/49 (10.2%)

3/25 (12%)

2/24 (8.3%)

Ahmed, N [116]

30/182 (16.4%)

14/87 (16%)

16/95 (16.8%)

Anter, A [117]

12/100 (12%)

NA

NA

Badr, H [118]

1/39 (2.5%)

0/20

1/19 (5.3%)

Bajwah,S [119]

6/53 (11.3%)

3/26 (11.5%)

3/27 (11.1%)

Bakitas, M [120]

94/207 (45.4%)

45/104 (43.2%)

49/103 (47.5%)

Berwouts, D [121]

2/45 (4.4%)

2/30 (6.6%)

0/15

Buckingham, S [122]

13/32 (40.6%)

8/24 (33%)

5/8 (62%)

Chan, K [123]

20/29 (69%)

10/14 (71%)

10/15 (66%)

Currow, D [124]

19/106 (18%)

7/52 (13.4%)

12/54 (22.2%)

Davies, H [125]

10/106 (9.4%)

7/54 (13%)

3/52 (5.8%)

Eguchi,K [126]

1/35 (3%)

0/18

1/17 (6%)

Eldeeb, N [127]

NA

NA

NA

Fallon, M [128]

56/233 (24%)

32/116 (27.5%)

24/117 (20.5%)

Hardy, J [129]

NA

NA

NA

Higginson, I [130, 131]

23/105 (22%)

11/53 (20.7%)

12/52 (23%)

Higginson, I

6/52 (11.5%)

1/26 (3.8%)

5/26 (19.2%)

Hopp, F [132]

NA

NA

NA

Ibrahim, I [133]

1/39 (2.5%)

1/21 (5%)

0/28

Matlock, D [134]

10/51 (19.6%)

8/25 (32%)

2/26 (8%)

Jensen, W [135]

5/26 (19.2%)

3/13 (23%)

2/13 (15%)

Jacobs, C [136]

12/73 (16.4%)

6/38 (15.8%)

6/35 (17.1%)

Jatoi, A [137]

NA

NA

NA

Kwekkeboom, K [138]

8/86 (9.3%)

7/43 (16%)

1/43 (2.3%)

Li,F [139]

9/84 (10.7%)

2/28 (7.1%)

7/56 (12.5%)

Lund Rasmussen, C [140]

28/72 (38.8%)

13/34 (38.2%)

15/38 (39.4%)

Maddocks,M [141]

21/49 (42.8%)

15/30 (50%)

6/19 (31.5%)

Maltoni, M [142]

78/207 (37.7%)

35/100 (35%)

43/107 (40.1%)

McMillan, S [143]

366/716 (51%)

NA

NA

Nava, S [144]

11/200 (5.5%)

11/99 (11%)

0/101 (0%)

Nilssom,S [145]

23/100 (23%)

15/51 (29.4%)

8/49 (16.3%)

Okur,E [146]

1/48 (2%)

1/24 (4%)

0/24

Ozkul,S [147]

NA

NA

NA

Rief, H [148]

24/60 (40%)

12/30 (40%)

12/30 (40%)

Saha, A [149]

0/40

0/20

0/20

Sau,S [150]

NA

NA

NA

Steel,J [151]

140/261 (53.6%)

76/144 (53%)

64/117 (55%)

Wadhwa, D [152]

NA

NA

NA

Warth, M [153]

16/84 (19%)

4/42 (9.5%)

12/42 (28.5%)

Warth, M [154]

11/84 (13%)

3/42 (7.1%)

8/42 (19%)

Xue,D [155]

NA

NA

NA

Yousef, A [156]

0/120

0/60

0/60

Tarumi, Y [157]

18/74 (24.3%)

10/35 (28.6%)

8/39 (20.5%)

Mc Corke,R [158]

54/146 (37%)

30/66 (45.4%)

24/80 (30%)

Allen,R [159]

25/45 (55%)

16/22 (73%)

9/23 (39.1%)

Wong, F [160]

16/84 (19%)

6/43 (14%)

10/41 (24.3%)