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Table 4 Most common “As Needed” drug subgroup at admission (T0) and the day of death (T1)

From: Prescription trends at the end of life in a palliative care unit: observational study

ATC-code

Drug subgroup

Prescription “as needed”

p-value a

T0

T1

n (%)

n (%)

N02A

Opioid analgesics

88 (76.5)

106 (92.2)

0.001b

N02B

Non-opioid analgesics and antipyretics

52 (45.2)

57 (49.6)

0.552

A06A

Drugs for constipation

41 (35.7)

34 (29.6)

0.324

A03F

Propulsives

29 (25.2)

44 (38.3)

0.032b

N05C

Hypnotics

24 (20.9)

32 (27.8)

0.215

N05A

Antipsychotics

23 (20.0)

74 (64.3)

< 0.001b

A10A

Insulins and analogues

17 (14.8)

7 (6.1)

0.031b

N05B

Anxiolytics

16 (13.9)

43 (37.4)

< 0.001

A04A

Antiemetics and antinauseants

9 (7.8)

5 (4.3)

0.289

A03B

Belladonna and derivatives, plain

4 (3.5)

25 (21.7)

< 0.001b

A02B

Drugs for peptic ulcer and gastro-oesophageal reflux disease

2 (1.7)

0

C09A

Angiotensin-converting enzyme inhibitors, plain

2 (1.7)

1 (0.9)

1.000

M01A

Antiinflammatory and antirheumatic products, non-steroids

1 (0.9)

2 (1.7)

1.000

B02A

Antifibrinolytics

1 (0.9)

5 (4.3)

0.219

A07D

Antipropulsives

0

2 (1.7)

  1. T0- at admission. T1- the day of death. ATC- the Anatomical Therapeutic Chemical Code
  2. aMcNemar Test
  3. bstatistically significant at 5%