Trajectories of Health-related quality of life in patients with Advanced Cancer during the Last Year of Life: findings from the COMPASS study

Table 3 Association^a of the delineated trajectories with healthcare utilization during the last year of life and place of death ^b

	Number of hospital admissions 1 (Range: 0–14; Median: 3) (N = 333)		Total length of hospital stay 1 (Range: 0–122; Median: 18) (N = 333)		More than 1 emergency department visit 2 (N = 333)		Place of death [Ref: Hospital] 3 (N = 268)
					More than 1 emergency department visit 2 (N = 333)		Home		Hospice/ Care home
	Coef. (Std. Err.)	[95% CI]	Coef. (Std. Err.)	[95% CI]	Coef. (Std. Err.)	[95% CI]	Coef. (Std. Err.)	[95% CI]	Coef. (Std. Err.)	[95% CI]
Overall High HrQoL [Reference]
Progressively Decreasing HrQoL	0.01 (0.09)	[-0.16, 0.17]	0.01 (0.12)	[-0.23, 0.25]	-0.22 (0.26)	[-0.72, 0.29]	0.48 (0.34)	[-0.19, 1.16]	0.77 (0.54)	[-0.28, 1.82]
Asymmetric Decline in HrQoL	-0.29* (0.13)	[-0.55, -0.04]	-0.22 (0.17)	[-0.56, 0.12]	-0.60 (0.36)	[-1.31, 0.11]	0.83 (0.46)	[-0.07, 1.74]	1.68* (0.55)	[0.61, 2.76]
Overall Low HrQoL	0.09 (0.14)	[-0.19, 0.37]	0.47* (0.21)	[0.06, 0.89]	0.02 (0.43)	[-0.83, 0.87]	-0.64 (0.81)	[-2.23, 0.95]	1.86* (0.66)	[0.57, 3.16]

* Statistically significant at the 5% level
¹ Negative binomial regression, 2 Logistic regression, 3 Multinomial logistic regression
^a All estimates were adjusted for age at beginning of last year of life, gender, marital status and highest educational attainment
^b Subsample of participants who died before October 2019
^† Coef.: Coefficient; Std. Err: Standard Error, CI: Confidence Interval; HrQoL: Health-related Quality of Life

ISSN: 1472-684X