Table 3 Multilevel modeling of psychobiological data
Fixed effects | M1: sCort (covariates) | M2: sCort (+ treatment) | M3: sAA (covariates) | M4: sAA (+ treatment) | ||||
|---|---|---|---|---|---|---|---|---|
Est | p | Est | p | Est | p | Est | p | |
INTERCEPT | 0.821 | 0.000 | 0.974 | 0.000 | 4.679 | 0.000 | 4.745 | 0.000 |
SEQUENCE (0 = MI—> CC, 1 = CC—> MI) | -0.106 | 0.639 | -0.145 | 0.506 | -0.124 | 0.669 | -0.206 | 0.459 |
TIME (linear: 0, 1, 2, 3) | -0.033 | 0.013 | -0.048 | 0.009 | 0.010 | 0.732 | 0.028 | 0.484 |
TREAT (0 = CC, 1 = MI) | - | - | -0.048 | 0.678 | - | - | -0.037 | 0.799 |
SEX (0 = male, 1 = female) | - | - | - | - | -0.826 | 0.010 | -0.761 | 0.015 |
MED.SEDA (0 = no, 1 = yes) | 0.691 | 0.038 | 0.682 | 0.035 | - | - | - | - |
MED.CORT (0 = no, 1 = yes) | -0.920 | 0.030 | -0.820 | 0.035 | - | - | - | - |
TIME SINCE LAST MEAL (minutes) | 0.001 | 0.002 | 0.001 | 0.001 | - | - | - | - |
TIME*TREAT | - | - | 0.032 | 0.214 | - | - | -0.015 | 0.798 |
Random effects (variances) | ||||||||
  INTERCEPT L3 (across patients) | 0.303 | - | 0.271 | - | 0.631 | - | 0.613 | - |
  INTERCEPT L2 (across sessions) | 0.186 | - | 0.198 | - | 0.189 | - | 0.200 | - |
  Residual variance | 0.057 | - | 0.059 | - | 0.331 | - | 0.334 | - |
Model fit | ||||||||
  AIC | 244.104 | - | 271.232 | - | 728.881 | - | 771.726 | - |
  BIC | 276.688 | - | 311.973 | - | 755.215 | - | 806.027 | - |
N | ||||||||
  Observations (L1) | 276 | - | 300 | - | 318 | - | 334 | - |
  Sessions (L2) | 69 | - | 75 | - | 80 | - | 84 | - |
  Patients (L3) | 38 | - | 38 | - | 40 | - | 42 | - |