1. History of primary or metastatic bone cancer diagnosed using imaging and physical examination |
2. Presence of continuous, background pain (usually described as annoying, dull, gnawing, aching, and/or nagging) in 1 or more locations generally consistent with known distribution of bone lesions |
3. Presence of evoked or spontaneous pain (often described as electric or shock-like) in 1 or more locations generally consistent with known distribution of bone lesions, associated with weight bearing or movement or can occur spontaneously |
4. Clinical examination over the site of pain reveals: • Hyperalgesia to blunt, non-noxious pressure or pin-prick stimuli • Hypoesthesia to non-noxious thermal stimuli • Hypoesthesia to light touch stimuli |