Table 3 Bivariate and adjusted regression coefficients with 95% confidence interval (95%CI) for associations between QoL and symptom burden adjusted for sociodemographic factors, medical factors, and analgesic use

Variable

B

β

p

B

95% CI

β

p

Global QoL [constant]

82.509

[76.76, 88.26]

Number of symptoms

-1.201

− 0.389

< 0.001

− 0.171

[-0.675, 0.333]

− 0.055

0.503

Physical symptoms

-27.634

− 0.617

< 0.001

-24.363

[-32.172, -16.555]

− 0.544

< 0.001

Psychological symptoms

-12.467

− 0.341

< 0.001

− 0.688

[-6.656, 5.279]

0.019

0.820

Age (years)

0.200

0.065

0.443

Highest educational level (elementary school/high school)

− 0.606

− 0.012

0.895

Highest educational level (elementary school/ university)

-4.917

− 0.100

0.275

Time since metastatic disease (in months)

0.040

0.042

0.622

PSA (ng/ml)

− 0.021

− 0.209

0.012

− 0.015

[-0.028, − 0.001

− 0.143

0.033

Analgesic use

-9.902

− 0.223

0.007

-6.767

[-12.486, -1.048]

− 0.153

0.021