Factor | Relaxed rule-based criteria | Strict rule-based criteria | |||
---|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | ||
Age | < 65 | - | 0.182 | - | 0.003 |
≥ 65 | 1.08 (0.96–1.21) | 1.18 (1.02–1.37) | |||
Sex | Female | - | 0.002 | - | 0.937 |
Male | 1.25 (1.08–1.43) | 1.00 (0.84–1.2) | |||
Disease | Breast | Ref | < 0.001 | ref | < 0.001 |
Endocrine | 0.93 (0.53–1.58) | 0.740 (0.32–1.38) | |||
Gastrointestinal | 0.78 (0.63–0.97) | 0.60 (0.46–0.79) | |||
Gynecological | 0.78 (0.68–1.02) | 0.57 (0.44–0.74) | |||
Hematological | 0.81 (0.62–1.07) | 0.93 (0.67–1.28) | |||
Head and neck | 0.87 (0.68–1.11) | 0.47 (0.33–0.65) | |||
Male genitals | 0.53 (0.35–0.80) | 0.58 (0.35–0.96) | |||
Mesothelial and soft tissue | 1.78 (1.11–2.83) | 1.73 (0.99–2.93) | |||
Other | 1.01 (0.57–1.73) | 1.38 (0.72–2.54) | |||
Respiratory and intrathoracic organs | 1.51 (1.19–1.91) | 1.14 (0.86–1.52) | |||
Skin | 2.48 (1.52–3.98) | 3.21 (1.87–5.38) | |||
Urinary tract | 0.60 (0.39–0.91) | 0.55 (0.31–0.93) | |||
Stage | 1 | ref | < 0.001 | ref | < 0.001 |
2 | 1.33 (1.08–1.63) | 1.38 (1.04–1.83) | |||
3 | 1.65 (1.36–1.99) | 1.58 (1.21–2.07) | |||
4 | 2.76 (2.29–3.32) | 3.00 (2.34–3.91) | |||
Pain | No | < 0.001 | < 0.001 | ||
Yes | 2.38 (2.13–2.66) | 1.69 (1.46–1.96) | |||
Dyspnea | No | < 0.001 | < 0.001 | ||
Yes | 4.30 (3.79–4.88) | 3.11 (2.67–3.63) | |||
Edema | No | < 0.001 | < 0.001 | ||
Yes | 1.63 (1.33–1.99) | 1.61 (1.28–2.01) | |||
Delirium | No | < 0.001 | < 0.001 | ||
Yes | 3.17 (1.70–5.88) | 3.52 (1.80–6.63) | |||
Xerostomia | No | 0.005 | < 0.001 | ||
Yes | 1.68 (1.17–2.42) | 2.50 (1.73–3.60) | |||
Ascites | No | 0.035 | 0.459 | ||
Yes | 0.81 (0.67–0.98) | 0.91 (0.71–1.16) | |||
Dysphagia | No | < 0.001 | 0.138 | ||
Yes | 2.46 (2.06–2.94) | 0.81 (0.61–1.06) | |||
Anorexia | No | < 0.001 | < 0.001 | ||
Yes | 2.23 (1.90–2.62) | 2.00 (1.66–2.43) |